Popularly referred to as “Big Data,” mammoth sets of information about almost every aspect of our lives have triggered great excitement about what we can glean from analyzing these diverse data sets. Benefits range from better investment of resources, whether for government services or for sales promotions, to more effective medical treatments. However, real insights can be obtained only from data that are accurate and complete.
While maps can certainly enlighten and educate, they can just as easily be used to support certain political narratives. With this in mind, Durham University’s Centre for Borders Research (IBRU) has updated its map showing territorial claims to the Arctic seabed following a revised bid submitted by Russia to the United Nations on August 4, 2015. The decision to release the map was not made lightly.
Andy Weir is used to living on different worlds. For years, he pictured Martian landscapes in his mind, complete with all of the deadly threats presented by a planet bathed in radiation and the prospect that a human walking about would die in a very, very short time. Weir imagined just what would happen when an astronaut was accidentally left behind on a mission to the Red Planet. What would this astronaut have to do to survive?
The American Midwest has recently seen significant precipitation and two major floods — in 1998 and 2008 — from extraordinary rain falls across the Great Plains. What is causing this dramatic change in weather patterns? Is it the warming planet? Are the crops themselves influencing dramatic weather changes taking place over the last couple decades? HPC clusters at ISU are being used to help discover answers to these questions.
DOE was used to demonstrate that temperature and pH function synergistically in the process of peptide bond formation. The optimized reaction was used to achieve sequence-specific and nonracemized synthesis of a tetrapeptide and pentapeptide at high yields. This is believed to be the first published report of constructing sequence-specific peptides in a noncatalyzed reaction.
Researchers have discovered one of nature’s strongest mechanical bonds on a protein network called cellulosomes. The cellulosome network includes bacteria that contain enzymes that can effectively dismantle cellulose and chemically catalyze it. The discovery was aided by use of supercomputers to simulate interactions at the atomic level.
It’s been 50 years since Gordon Moore, one of the founders of the microprocessor company Intel, gave us Moore’s Law. This says that the complexity of computer chips ought to double roughly every two years. Now the current CEO of Intel, Brian Krzanich, is saying the days of Moore’s Law may be coming to an end as the time between new innovation appears to be widening.
The TOP500 project was started in 1993 to provide a reliable basis for tracking and detecting trends in high-performance computing. Twice a year, a list of the sites operating the 500 most powerful computer systems is assembled and released. The best performance on the Linpack benchmark is used as a performance measure for ranking the computer systems.
The TOP500 list provides international rankings of general-purpose HPC systems that are in common use for high-end applications. Twice a year, in June and November, a new list featuring the sites operating the 500 most powerful computer systems is assembled and released. The project was started in 1993 to provide a reliable basis for tracking and detecting trends in high-performance computing.
Optimization of workflows in a modern HPC environment is now a globally distributed, heterogeneous-hardware-challenged task for users and systems administrators. Not only is this a mouthful to say, it is also a complex task that requires significant software support.
As the HPC community hurtles toward the exascale era, it’s good to pause and reflect. Here are a few thoughts… The DOE CORAL procurement signaled that extreme-performance supercomputers from the U.S., Japan, China and Europe should reach the 100-300PF range in 2017-2018. That’s well short of DOE’s erstwhile stretch goal of deploying a trim, energy-efficient peak exaflop system in 2018 or so, but still impressive. It would appear...
Your corresponding editor really loves to review these genomics programs, as genomics (the study of the entire gene complement in an organism) is his area of research, and an exciting one at that. It is now at the center of a cutting-edge movement within the area of personalized medicine. The software for doing this is highly advanced in that its functioning mates the precision of mathematics/statistics with the variability of biology...
Life scientists are increasingly reliant on advanced computation to advance their research. Two very prominent examples of this trend will be presented this summer at the ISC High Performance conference, which will feature a five-day technical program focusing on HPC technologies and their application in scientific fields, as well as their adoption in commercial environments.
This new series of four articles takes a look at the UK’s Medicines and Heathcare products Regulatory Agency (MHRA) guidance for industry on data integrity. The focus of these articles is an interpretation and critique of the second version of the MRHA data integrity guidance for laboratories working to European Union GMP regulations, such as analytical development in R&D and quality control in pharmaceutical manufacturing.
Over 75 percent of a laboratory experiment or analysis starts with some kind of manual process, such as weighing. The majority of the results of these measurements are still written down manually on a piece of paper or re-typed into a computer or tablet. ELN and mobile devices like tablets are married to each other. However, to connect a balance, you need to be an IT professor...