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New opportunities for covalent drugs published by Avila scientists

Avila Therapeutics published a scientific article in Nature Reviews Drug Discovery titled "The Resurgence of Covalent Drugs." This article discusses the broad opportunities for covalent drugs and how structural bioinformatics coupled with structure-based drug design can enable the design of highly selective covalent drugs with unique therapeutic properties for treating a variety of diseases. It examines the prevalence of covalent drugs, mechanistic and pharmacological features, and approaches to design and optimization of targeted covalent inhibitors.

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