Fossil remains of a previously unknown species of a crocodile-like "super salamander" that grew as long as a small car and was a top predator more than 200 million years ago have been found in southern Portugal, researchers announced on March 24, 2015. The prehistoric species, which looked like giant salamanders, grew up to six feet in length and lived in lakes and rivers.
In 1996, a trio of scientists won the Nobel Prize for Chemistry for their discovery of...
Breaking new grounds in the future of remote-controlled drone technology, researchers have...
Solving Puzzle-Like Bond for Biofuels: First Look at One of Nature's Strongest Biomolecular InteractionsMarch 17, 2015 3:02 pm | by Texas Advanced Computing Center | News | Comments
One of life's strongest bonds has been discovered by a science team researching biofuels with...
A means of reprogramming a flawed immune response into an efficient anti-tumoral one was brought to light by the results of a translational trial relating to breast cancer. Thanks to the innovative combination of mathematical modeling and experimentation, only 20 tests were necessary, whereas traditional experimentation would have required 596 tests to obtain the same results.
University of Pittsburgh, Carnegie Mellon University, UPMC Form Alliance to Transform Healthcare through Big DataMarch 17, 2015 2:19 pm | by UPMC | News | Comments
Today’s health care system generates massive amounts of data — electronic health records, diagnostic imaging, prescriptions, genomic profiles, insurance records, even data from wearable devices. Information has always been essential for guiding care, but computer tools now make it possible to use that data to provide deeper insights. Leveraging big data to revolutionize healthcare is the focus of the Pittsburgh Health Data Alliance.
Researchers have achieved the first “image fusion” of mass spectrometry and microscopy — a technical tour de force that could, among other things, dramatically improve the diagnosis and treatment of cancer. Using a mathematical approach called regression analysis, they mapped each pixel of mass spectrometry data onto the corresponding spot on the microscopy image to produce a new, “predicted” image.
Studying the intricate fractal patterns on the surface of cells could give researchers a new insight into the physical nature of cancer, and provide new ways of preventing the disease from developing. This is according to scientists who have, for the first time, shown how physical fractal patterns emerge on the surface of human cancer cells at a specific point of progression towards cancer.
A high-speed camera for monitoring vegetation from space and combating famine in Africa is being adapted to spot changes in human skin cells, invisible to the naked eye, to help diagnose skin diseases like cancer. In fact, the extraordinary digital infrared sensor from ESA’s Proba-V vegetation-scanning satellite is being adapted for several non-space applications.
For the first time, researchers have produced a 3-D image revealing part of the inner structure of an intact, infectious virus, using a unique X-ray laser. The virus, called Mimivirus, is in a curious class of “giant viruses” discovered just over a decade ago. The experiment establishes a new technique for reconstructing the 3-D structure of many types of biological samples from a series of X-ray laser snapshots.
Researchers focusing on a fictional zombie outbreak as an approach to disease modeling suggest heading for the hills, in the Rockies, to save your brains from the undead. Reading World War Z: An Oral History of the First Zombie War, and taking a graduate statistical mechanics class inspired a group of Cornell University researchers to explore how an "actual" zombie outbreak might play out in the U.S.
Pull on a piece of plastic at separate ends; it becomes thinner. So does a rubber band. One might assume tha,t when a force is applied along an axis, materials will always stretch and become thinner. Wrong. Thanks to their peculiar internal geometry, auxetic materials grow wider. After confounding scientists for decades, researchers are now developing mathematical models to explain the unusual behavior of these logic-defying materials
Three Austrians have replaced injured hands with bionic ones that they can control using nerves and muscles transplanted into their arms from their legs. The men are the first to undergo what doctors refer to as "bionic reconstruction," which includes a voluntary amputation, the transplantation of nerves and muscles and learning to use faint signals from them to command the hand.
Researchers have developed a novel three-dimensional, multiscale and multicomponent model of the endothelial cell monolayer, the inner lining of the artery, to identify the cellular mechanisms involved in cardiovascular diseases. New research based on the model is able to identify the main cellular pathways involved in the initiation and progression of the disease.
A new mathematical analysis tool has allowed a deeper understanding of the anatomy of the human head, describing the skull as an extended network structured in 10 modules. Researchers have developed a research methodology called Anatomical Network Analysis (AnNA), based on network analysis mathematical tools for studying anatomy.
Qlucore Omics Explorer 3.1 advanced data analysis software features a well-defined open interface to R. The interface allows users to utilize a broad range of statistical tests, to use existing tests in R, and to write new ones. The inbuilt statistical functions of the bioinformatics program are extended with the R interface to include the full suite of statistical methods available in R.
For those on the front lines of treating cancer, speed and precision are key to patients’ survival. Pediatric cancer researchers have been making incredible strides in accelerating delivery of new diagnostic and treatment options. Supercomputer-powered genetic diagnosis is being used to harness the power of high throughput genomic and proteomic methods and is playing a key role in improving the outcome for children with genetic diseases.
Personal information taken from social media, blogs, page views and so on is used to detect disease outbreaks, but does this violate our privacy, consent and trust? Dr. Effy Vayena from the University of Zurich and colleagues have mapped the numerous ethical challenges confronting digital disease detection and propose a framework to address the questions.
The author of this wonderful text delivers a brief, easy-to-absorb, yet very comprehensive text on modeling real-world data with Maple. Maple is software for performing mathematics, with a none-too-steep learning curve. In the introduction, the author is quick to point out that this is neither a detailed textbook of mathematical modeling, nor Maple. It is, however, a very well-written manual of introductory modeling and use of Maple.
Statistical decision making resembles a process Alan Turning's team did in Bletchley Park to work out the settings of German enigma machines. In order to make use of the large clicking machine, Turing's team analyzed pairs of randomly intercepted German messages, aligned them one above the other to accumulate evidence from letter pairs until they reach a threshold level of certainty that the messages were sent on identical enigma machine.
The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague. A pathogen map of a city provides a baseline assessment. Repeated sampling could be used for long-term, accurate disease surveillance, bioterrorism threat mitigation, and large-scale health management.
A team of researchers has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three HIV and syphilis infectious disease markers from a finger prick of blood in just 15 minutes. The device replicates, for the first time, all mechanical, optical and electronic functions of a lab-based blood test. Specifically, it performs an ELISA assay.
Top researchers are using mathematical modelling and heavy computations to understand how the brain can both remember and learn. Ten years ago, when the team of Marianne Fyhn and Torkel Hafting Fyhn cooperated with the Nobel Prize winning team of May-Britt and Edvard Moser at NTNU, they discovered the sense of orientation in the brain.
Scientists have identified a biological clock that provides vital clues about how long a person is likely to live. Researchers studied chemical changes to DNA that take place over a lifetime, and can help them predict an individual's age. By comparing individuals’ actual ages with their predicted biological clock age, scientists saw a pattern emerging.
The release of the film, Still Alice, in September 2014 placed a much-needed light on Alzheimer's disease, a debilitating neurological disease that affects a growing number of Americans each year. More than 5.2 million people in the U.S. are currently living with Alzheimer's. One out of nine Americans over 65 has Alzheimer's, and one out of three over 85 has the disease. For those over 65, it is the fifth leading cause of death.
Diabesity has been identified as a major global health problem by researchers and healthcare professionals world-wide, including England’s National Health Service, Brigham and Women’s Hospital and Harvard Medical School, Ain Shams University Hospital in Cairo, Egypt, and a research consortium of the European Union.
American leafminer moth Coptodisca lucifluella has been invading Italian walnut orchards since 2010. Interestingly, the moth lives on pecan trees in the United States, but invaded a new host plant in Europe: the walnut tree.
Quantum chemical calculations have been used to solve big mysteries in space. Soon the same calculations may be used to produce tomorrow’s cancer drugs. Quantum chemical calculations are needed to explain what happens to the electrons’ trajectories within a molecule, and the results of a quantum chemical calculation are often more accurate than what is achievable experimentally.
ACD/Labs 2015 cheminformatics software builds upon the capabilities of the ACD/Spectrus and ACD/Percepta platforms. The ACD/Spectrus Platform is designed to make it easier for organizations to handle unified analytical data from multiple techniques and instruments. The ACD/Percepta Platform features improvements in the speed of calculation of physicochemical and ADME-Tox properties and expanded capabilities to leverage organizational knowledge.
- Page 1