Researchers focusing on a fictional zombie outbreak as an approach to disease modeling suggest heading for the hills, in the Rockies, to save your brains from the undead. Reading World War Z: An Oral History of the First Zombie War, and taking a graduate statistical mechanics class inspired a group of Cornell University researchers to explore how an "actual" zombie outbreak might play out in the U.S.
Pull on a piece of plastic at separate ends; it becomes thinner. So does a rubber band. One...
Three Austrians have replaced injured hands with bionic ones that they can control using nerves...
Researchers have developed a novel three-dimensional, multiscale and multicomponent model of the...
A new mathematical analysis tool has allowed a deeper understanding of the anatomy of the human head, describing the skull as an extended network structured in 10 modules. Researchers have developed a research methodology called Anatomical Network Analysis (AnNA), based on network analysis mathematical tools for studying anatomy.
Qlucore Omics Explorer 3.1 advanced data analysis software features a well-defined open interface to R. The interface allows users to utilize a broad range of statistical tests, to use existing tests in R, and to write new ones. The inbuilt statistical functions of the bioinformatics program are extended with the R interface to include the full suite of statistical methods available in R.
For those on the front lines of treating cancer, speed and precision are key to patients’ survival. Pediatric cancer researchers have been making incredible strides in accelerating delivery of new diagnostic and treatment options. Supercomputer-powered genetic diagnosis is being used to harness the power of high throughput genomic and proteomic methods and is playing a key role in improving the outcome for children with genetic diseases.
Personal information taken from social media, blogs, page views and so on is used to detect disease outbreaks, but does this violate our privacy, consent and trust? Dr. Effy Vayena from the University of Zurich and colleagues have mapped the numerous ethical challenges confronting digital disease detection and propose a framework to address the questions.
The author of this wonderful text delivers a brief, easy-to-absorb, yet very comprehensive text on modeling real-world data with Maple. Maple is software for performing mathematics, with a none-too-steep learning curve. In the introduction, the author is quick to point out that this is neither a detailed textbook of mathematical modeling, nor Maple. It is, however, a very well-written manual of introductory modeling and use of Maple.
Statistical decision making resembles a process Alan Turning's team did in Bletchley Park to work out the settings of German enigma machines. In order to make use of the large clicking machine, Turing's team analyzed pairs of randomly intercepted German messages, aligned them one above the other to accumulate evidence from letter pairs until they reach a threshold level of certainty that the messages were sent on identical enigma machine.
The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague. A pathogen map of a city provides a baseline assessment. Repeated sampling could be used for long-term, accurate disease surveillance, bioterrorism threat mitigation, and large-scale health management.
A team of researchers has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three HIV and syphilis infectious disease markers from a finger prick of blood in just 15 minutes. The device replicates, for the first time, all mechanical, optical and electronic functions of a lab-based blood test. Specifically, it performs an ELISA assay.
Top researchers are using mathematical modelling and heavy computations to understand how the brain can both remember and learn. Ten years ago, when the team of Marianne Fyhn and Torkel Hafting Fyhn cooperated with the Nobel Prize winning team of May-Britt and Edvard Moser at NTNU, they discovered the sense of orientation in the brain.
Scientists have identified a biological clock that provides vital clues about how long a person is likely to live. Researchers studied chemical changes to DNA that take place over a lifetime, and can help them predict an individual's age. By comparing individuals’ actual ages with their predicted biological clock age, scientists saw a pattern emerging.
The release of the film, Still Alice, in September 2014 placed a much-needed light on Alzheimer's disease, a debilitating neurological disease that affects a growing number of Americans each year. More than 5.2 million people in the U.S. are currently living with Alzheimer's. One out of nine Americans over 65 has Alzheimer's, and one out of three over 85 has the disease. For those over 65, it is the fifth leading cause of death.
Diabesity has been identified as a major global health problem by researchers and healthcare professionals world-wide, including England’s National Health Service, Brigham and Women’s Hospital and Harvard Medical School, Ain Shams University Hospital in Cairo, Egypt, and a research consortium of the European Union.
American leafminer moth Coptodisca lucifluella has been invading Italian walnut orchards since 2010. Interestingly, the moth lives on pecan trees in the United States, but invaded a new host plant in Europe: the walnut tree.
Quantum chemical calculations have been used to solve big mysteries in space. Soon the same calculations may be used to produce tomorrow’s cancer drugs. Quantum chemical calculations are needed to explain what happens to the electrons’ trajectories within a molecule, and the results of a quantum chemical calculation are often more accurate than what is achievable experimentally.
ACD/Labs 2015 cheminformatics software builds upon the capabilities of the ACD/Spectrus and ACD/Percepta platforms. The ACD/Spectrus Platform is designed to make it easier for organizations to handle unified analytical data from multiple techniques and instruments. The ACD/Percepta Platform features improvements in the speed of calculation of physicochemical and ADME-Tox properties and expanded capabilities to leverage organizational knowledge.
Researchers were able to predict the interactions of cancer cells using a part of game theory known as the public goods game, suggesting that work on the social interactions among cancer cells may provide insight into the dynamics of cancer. Researchers applied this model to the cooperation between producing and non-producing members of a cancer cell population, in order to examine if the model is also applicable to biological processes.
A new online resource, called the Biosurveillance Gateway, is in place at Los Alamos National Laboratory, providing a centralized portal for all news, information, resources and research related to biosurveillance at the laboratory. The goal of the site is to support global disease surveillance, providing useful tools for professionals around the world to reference from a single location.
A team of scientists has received a $1.4 million grant from the National Science Foundation to help meet the growing needs of the data-driven genomic science community. The Tripal Gateway project will build on existing cyberinfrastructure to enhance the capacity of genomic databases to manage, exchange and process “big data.”
In the largest collaborative study of the brain to date, researchers from the Keck School of Medicine of the University of Southern California (USC) led a global consortium of 190 institutions to identify eight common genetic mutations that appear to age the brain an average of three years. The discovery could lead to targeted therapies and interventions for Alzheimer’s disease, autism and other neurological conditions.
The Biomolecule Toolkit is a Web service-based toolkit designed to bridge the gap between biology and chemistry for complex biomolecular entities. It provides unambiguous representation at the sequence and atomic level for a diverse set of biomolecules such as peptides, oligonucleotides, proteins and antibody drug conjugates, including those containing unnatural and chemically-modified components, thereby allowing their storage, indexing and search within a database.
Pope Francis, who pledged on the day of his installation as pontiff to make the environment a priority, is drafting a highly anticipated encyclical on ecology and climate change. Environmentalists are thrilled by the prospect of a rock-star pope putting his moral weight behind efforts to curb global warming. Francis said he wanted the document to be released in time to be read before the next round of U.N. climate treaty talks in Paris.
On Wednesday, January 21, Scientific Computing will host a live panel discussion that looks at how big data and data science have fast become the next frontier for innovation, competition and productivity. One of today’s significant advances in data science introduces us to the Next Generation Cyber Capability (NGCC) at Arizona State University (ASU)...
The human lament that things in the past were much simpler is an accurate observation made from the perspective of riding along an exponentially increasing complexity curve. Examining the present or looking into the future can be a confusing torrent of concepts, vocabulary and technologies that appear to be spiraling out-of-control. At the First IEEE Integrated STEM Education Conference, Professor Steve Zilora reflected on this increase...
A new technique to help surgeons find the exact location of heart defects could save lives, help them to treat patients more effectively and save health service cash. The development will allow non-invasive detection of the origin of heart problems and allow more effective treatment.
Scientists can now explore nerves in mice in much greater detail than ever before, thanks to an approach developed by scientists at the European Molecular Biology Laboratory. The work enables researchers to easily use artificial tags, broadening the range of what they can study and vastly increasing image resolution.
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