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Randy Hice is a leading authority in the field of laboratory informatics and currently works for a global healthcare company. He may be reached at editor@ScientificComputing.com.

Prostate Cancer Jungle: Navigating Diagnosis and Treatment Options is Daunting

May 28, 2015 4:47 pm | by Randy C. Hice | Blogs | Comments

What do Rudolph Guliani, Robert Diniro, Dennis Hopper, James Brown, Arnold Palmer, Joe Torre, Dan Fogelberg, Colin Powell, John Kerry, Johnny Ramone, Francois Mitterand, Robert Frost, and Frank Zappa have in common? They have lived with, or died from, prostate cancer. Every 19 minutes, an American man dies from prostate cancer. It is the second leading cause of cancer death among men and is the most common cancer in men...

Next-gen Neuroprosthetics: Clinical Trial Shows Intuitive Control of Robotic Arm Using Thought

May 22, 2015 11:02 am | by Alison Trinidad, University of Southern California - Health Sciences | News | Comments

Paralyzed from the neck down after suffering a gunshot wound when he was 21, Erik G. Sorto now...

Infections can affect your IQ

May 21, 2015 11:49 am | by Ingrid Marie Fossum, Aarhus University | News | Comments

Anyone can suffer from an infection, for example in their stomach, urinary tract or skin....

Age of Wearable Computing Delivers BioStamp Electronic Skin

May 20, 2015 3:32 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | News | Comments

MC10  is developing a technology that will allow digital circuits to be embedded in bendable,...

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Investigators have applied NetGestalt to data from The Cancer Genome Atlas (TCGA) colorectal cancer cohort, the first tumor dataset with complete molecular measurements at DNA, RNA and protein levels.

User-friendly Data Query, Visualization Tools Enable Omics Data Integration

May 19, 2015 4:21 pm | by Leigh MacMillan, Vanderbilt University | News | Comments

Advances in technology have generated vast amounts of “omics” data: genomic, epigenomic, transcriptomic, proteomic and metabolomic changes for all types of specimens. Bridging the gap between data generation and investigators’ ability to retrieve and interpret data is essential to realize the biological and clinical value of this wealth of information.

Scientists are now closer to imitating key electronic aspects of the human brain — a vital step towards creating a bionic brain.

Researchers take Vital Step toward Creating Bionic Brain

May 19, 2015 3:08 pm | by RMIT University | News | Comments

Researchers have mimicked the way the human brain processes information with the development of an electronic long-term memory cell, which mirrors the brain’s ability to simultaneously process and store multiple strands of information. The development brings them closer to imitating key electronic aspects of the human brain — a vital step toward creating a bionic brain and unlocking treatments for Alzheimer’s and Parkinson’s diseases.

BigNeuron, a new project led by the Allen Institute for Brain Science, aims to streamline scientist’s ability to create 3-D digital models of neurons. Courtesy of Allen Institute for Brain Science

Digitizing Neurons: Project will convert 2-D Microscope Images into 3-D Models

May 14, 2015 9:46 am | by Oak Ridge National Laboratory | News | Comments

A new initiative designed to advance how scientists digitally reconstruct and analyze individual neurons in the human brain will receive support from the supercomputing resources at the Department of Energy’s Oak Ridge National Laboratory (ORNL). Led by the Allen Institute for Brain Science, the BigNeuron project aims to create a common platform for analyzing the three-dimensional structure of neurons.

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The research team examined blood samples from 33 survivors of car or motorcycle accidents or falls for multiple markers of inflammation, including interleukin-6 (IL-6), and segregated the patients into one of three (low to high) categories of trauma sever

Computer Simulation Accurately Replicates Real-life Trauma Outcomes

May 13, 2015 2:03 pm | by University of Pittsburgh | News | Comments

Computer simulation of the body’s inflammatory response to traumatic injury accurately replicated known individual outcomes and predicted population results. Researchers examined blood samples from 33 survivors of car or motorcycle accidents or falls for multiple markers of inflammation, including interleukin-6, and segregated the patients into categories of trauma severity. They were able to validate model predictions.

Barcelona Biomedical Research Park (PRBB) in Catlonia, Spain

Designing and Managing the LIMS at Barcelona Biomedical Research Park's Animal Facility

May 7, 2015 8:18 am | by Helen Kelly | Articles | Comments

Today's LIMS allow research institutions to monitor and manage a broad array of biomedical research processes end-to-end and remotely. But how do they accommodate the ongoing flood of discoveries in areas such as genetics, the -omics, regenerative medicine and behavior, ongoing adjustments to workflows and protocols, tens of thousands of animals, and the evolution of legislative, welfare quality, and ethics directives?

The new program builds on IBM Research advancements in analytics and existing Watson collaborations to develop a genome data analysis solution for clinicians. Partners involved in the program will use Watson Genomic Analytics, a new solution specifically

14 Leading Cancer Institutes Collaborate to Advance Personalized Medicine for Cancer Patients

May 6, 2015 12:33 pm | by IBM | News | Comments

IBM Watson is collaborating with more than a dozen leading cancer institutes to accelerate the ability of clinicians to identify and personalize treatment options for their patients. The institutes will apply Watson's advanced cognitive capabilities to reduce from weeks to minutes the ability to translate DNA insights, understand a person's genetic profile and gather relevant information from medical literature to personalize treatment.

Scientists have programmed DNA to calculate multiple GPS routes at the same time. Courtesy of the American Chemical Society

Next Step in DNA Computing: GPS Mapping?

May 6, 2015 12:23 pm | by American Chemical Society | News | Comments

Conventional silicon-based computing, which has advanced by leaps and bounds in recent decades, is pushing against its practical limits. DNA computing could help take the digital era to the next level. Scientists are now reporting progress toward that goal with the development of a novel DNA-based GPS.

This four-second time-lapse photo of a Los Angeles freeway illustrates the complexities of decision-making, as one driver appears to have made a late change of mind while most drivers decided in advance whether to stay on the main road or take an exit ram

Mind Reading: Algorithm Enables Moment-by-moment Analysis of Brain Activity

May 6, 2015 12:01 pm | by Janet Rae-Dupree and Tom Abate, Stanford University | News | Comments

Researchers studying how the brain makes decisions have, for the first time, recorded the moment-by-moment fluctuations in brain signals that occur when a monkey making free choices has a change of mind. The findings result from experiments led by electrical engineering Professor Krishna Shenoy, whose Stanford lab focuses on movement control and neural prostheses — such as artificial arms — controlled by the user's brain.

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Another dimension: Professor Marc in het Panhuis (left) and Ph.D. student Shannon Bakarich are building objects using 4D printing, where time is the fourth dimension.

4D Printing, where Time — actually Shape Shifting — is the 4th Dimension

April 24, 2015 2:01 pm | by University of Wollongong | News | Comments

Just as the extraordinary capabilities of 3D printing have begun to infiltrate industry and the family home, researchers have started to develop 3D printed materials that morph into new structures post production, under the influence of external stimuli, such as water or heat — hence the name, 4D printing.

GenomeStack Big Data Analytics Database

GenomeStack Big Data Analytics Database

April 22, 2015 2:52 pm | by SQream Technologies | Product Releases | Comments

The GenomeStack Big Data Analytics platform has been developed specifically for bioinformatics researchers, data scientists and analysts conducting genome research. The database replaces the traditional file-based, manual process for storing and analyzing genome sequenced data.

Through special environments called biotic processing units, bioengineers allow people to interact with cells like fish in an aquarium or even do simple experiments from afar.

Biotic Processing Makes Biotech Interactive with Games, Remote-control Labs

April 22, 2015 2:10 pm | by Tom Abate, Stanford Engineering | News | Comments

Riedel-Kruse and his team are enabling people to interact with biological materials and perform experiments the way they interact with computers today — called interactive biotechnology.  They have created three related projects that begin to define this new field. In the most far-reaching project, Riedel-Kruse created a robotic biology cloud lab capable of carrying out remote-control experiments.

Power networks and cancer treatment are two of the applications for the dynamic, scalable algorithms that Frank E. Curtis has developed. Courtesy of Ryan Hulvat

Algorithms: Finding Optimal Balance in the Face of Uncertainty

April 21, 2015 12:20 pm | by Kurt Pfitzer, Lehigh University | News | Comments

Curtis writes algorithms that enable computers to solve large-scale continuous optimization problems. He is collaborating with researchers at Argonne through a five-year Early Career Award from the U.S. Department of Energy. In a three-year single-investigator project for the NSF, Curtis has developed algorithms that solve large-scale continuous optimization problems in less than a quarter of the time required by conventional methods.

Trish Meek is Director of Product Strategy at Thermo Fisher Scientific.

The Case for User-Friendly Informatics in the Pharmaceutical QA/QC Lab

April 20, 2015 9:32 am | by Trish Meek, Thermo Fisher Scientific | Articles | Comments

All the computing power in the world isn’t useful if the software designed to access it is poorly designed. And we’re all much more discerning about user interfaces and usability: we expect our laboratory software to behave as intuitively as our smartphones. After all, laboratory employees are unlikely to be preoccupied with lines of codes and processors — they’re focused more on how easy the software is to use.

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The future of tropical rainforests in the Amazon and worldwide is the focus of a new research project that combines field experiments and predictive modeling.

Study Combines Field Experiments, Predictive Modeling to Look at How Forests Worldwide Respond to Climate Change

April 7, 2015 5:09 pm | by Oak Ridge National Laboratory | News | Comments

Researchers from the Department of Energy’s Oak Ridge National Laboratory will play key roles in an expansive new project that aims to bring the future of tropical forests and the climate system into much clearer focus by coupling field research with the development of a new ecosystem model.

A supercomputer that can do 551 trillion calculations per second is housed at Clemson’s Information Technology Center.

Data-enabled Science: Top500 Supercomputers Provide Universities with Competitive Edge

April 7, 2015 5:02 pm | by Paul Alongi, Clemson University | News | Comments

Researchers have long believed that supercomputers give universities a competitive edge in scientific research, but now they have some hard data showing it’s true. A Clemson University team found that universities with locally available supercomputers were more efficient in producing research in critical fields than universities that lacked supercomputers.

Scanning electron microscope image of the one-micrometer thick nanocoatings on a silicon substrate

Phase-change Heat Transfer: Viruses Help Water Blow off Steam 3X Faster

April 7, 2015 12:14 pm | by Drexel University | News | Comments

Legions of viruses that infect the leaves of tobacco plants could be the key to making power plants safer, heating and cooling buildings more efficient and “really kick-ass computers,” or to the liquid cooling of high-powered electronic devices, like radar systems. These tiny protein bundles, which were once a threat to a staple cash crop, are now helping researchers better understand the processes of boiling and condensation. 

To demonstrate how neuroelectro.org could be used, the researchers compared electrophysiological data from more than 30 neuron types that had been most heavily studied in the literature. The site was able to find many expected similarities between the dif

Researchers Create Wikipedia for Neurons

April 7, 2015 11:11 am | by Jocelyn Duffy, Carnegie Mellon University | News | Comments

The decades worth of data collected about the billions of neurons in the brain is astounding. To help scientists make sense of this “brain big data,” researchers at Carnegie Mellon University have used data mining to create a publicly available Web site that acts like Wikipedia, indexing physiological information about neurons. The site will help to accelerate the advance of neuroscience research by providing a centralized resource.

UNSW Professor Melissa Knothe Tate is leading the project, which is using semiconductor technology to explore osteoporosis and osteoarthritis. Courtesy of Grant Turner/Mediakoo.

Previously Top-secret Technology enables Whole-body “Google Maps”

April 7, 2015 11:00 am | by UNSW Australia | News | Comments

A world-first collaboration uses previously top-secret technology to zoom through the human body down to the level of a single cell and could be a game-changer for medicine. UNSW Australia's Professor Tate is first to use the system in humans. She has forged a pioneering partnership with the US-based Cleveland Clinic, Brown and Stanford Universities, as well as Zeiss and Google to help crunch terabytes of data gathered from human study.

Cutting-edge brain research is helping some people with paraplegia walk and helping some blind people see. Courtesy of the National Science Foundation

Exploring the Unknown Frontier of the Brain

April 6, 2015 3:56 pm | by James L. Olds, National Science Foundation | Blogs | Comments

To a large degree, your brain is what makes you... you. It controls your thinking, problem solving and voluntary behaviors. At the same time, your brain helps regulate critical aspects of your physiology, such as your heart rate and breathing. And yet your brain — a nonstop multitasking marvel — runs on only about 20 watts of energy, the same wattage as an energy-saving light bulb.

Genomics processing is now moving mainstream to clinical applications, as new approaches to diagnosing and treatment involving genomics are gaining interest.

Efficient, Time Sensitive Execution of Next-gen Sequencing Pipelines Critical for Translational Medicine

April 6, 2015 3:26 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments

Demand for genomics processing is rapidly spreading from research labs to the clinical arena. Genomics is now a "must have" tool for researchers in areas of oncology and rare diseases. It is also becoming a requirement in the clinical space for precision medicine, translational medicine and similar "bench to bedside" initiatives.

New research has demonstrated that an amputee can grasp with a bionic hand, powered only by his thoughts.

Bionic Hand is Powered only by Thoughts

April 2, 2015 9:53 am | by Jeannie Kever, University of Houston | News | Comments

Researchers have created an algorithm that allowed a man to grasp a bottle with a prosthetic hand powered only by his thoughts. The technique, demonstrated with a man whose right hand had been amputated, uses non-invasive brain monitoring, capturing brain activity to determine what parts of the brain are involved in grasping an object. A computer program, or brain-machine interface (BMI), harnessed the subject’s intentions...

Figure d (left) shows a representative x-y projected brain vasculature image through an intact skull. Figure e shows a representative enhanced x-z projected brain vasculature image. Figure f shows photoacoustic microscopy of oxygen saturation of hemoglobi

Photoacoustic Method allows Rapid Imaging of Living Brain Functions

April 1, 2015 12:11 pm | by Beth Miller, Washington University in St. Louis | News | Comments

Researchers studying cancer and other invasive diseases rely on high-resolution imaging to see tumors and other activity deep within the body's tissues. Using photoacoustic microscopy, a single-wavelength, pulse-width-based technique, they were able to see blood flow, blood oxygenation, oxygen metabolism and other functions inside a living mouse brain at faster rates than ever before.

We can now use a very fast and biologically relevant computational model to study deforming structures of the clots growing in blood flow. The new model may be adapted to study clot formation in blood vessels, which can pose the risk of detaching and migr

Simulating Biofilm Mechanical Behavior Aids Blood Clotting Studies

April 1, 2015 11:47 am | by Gene Stowe, University of Notre Dame | News | Comments

Researchers have developed a new computational model that effectively simulates the mechanical behavior of biofilms. Their model may lead to new strategies for studying a range of issues from blood clots to waste treatment systems. The new model may be adapted to study clot formation in blood vessels, which can pose the risk of detaching and migrating to the lungs, a fatal event.

Omics Explorer 3.1 for Mac

Omics Explorer 3.1 for Mac

April 1, 2015 11:18 am | Qlucore AB | Product Releases | Comments

Qlucore Omics Explorer 3.1 for Mac is data analysis software designed to maximize the outcome of research by making it easy to analyze experiment data from a biological point-of-view. Examples of this are the inbuilt Gene Ontology (GO) Browser, a Gene Set Enrichment Analysis (GSEA) function, and freedom to explore data using any variable identifier: variable collapse.

Researchers have harnessed bionanotechnology to emit a full range of colors in one pliable pixel layer — as opposed to the several rigid layers that constitute today's screens.

From Genes to Screens: Molecular Backbone of Super-Slim, Bendable Digital Displays Developed

March 31, 2015 11:44 am | by Tel Aviv University | News | Comments

A new study suggests that a novel DNA-peptide structure can be used to produce thin, transparent and flexible screens. The research harnesses bionanotechnology to emit a full range of colors in one pliable pixel layer — as opposed to the several rigid layers that constitute today's screens.

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