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Big Data Approach to Bioinformatics Profiling Identifies New Mammalian Clock Gene

April 22, 2014 6:37 pm | by Penn Medicine | News | Comments

Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans. Over 15 mammalian clock proteins have been identified, but researchers surmise there are more. A team from the Perelman School of Medicine at the University of Pennsylvania wondered if big-data approaches could find them.

Alzheimer's-Cancer Link found using Biomedical Data, Supercomputing

April 22, 2014 3:35 pm | by Jorge Salazar, TACC | News | Comments

A team led by Houston Methodist Research Institute (HMRI) scientists has found that Alzheimer's...

Exciting Advances: Growth of HPC in the Life Sciences

April 18, 2014 3:12 pm | by Andrew Purcell | Articles | Comments

Manuel Peitsch, co-founder of the Swiss Institute of Bioinformatics, will chair a session on...

Understanding the Brain Site Features Funding Opportunities, Research across All Areas of Science

April 11, 2014 10:13 am | by NSF | News | Comments

On the first anniversary of President Obama's BRAIN Initiative announcement, the National...

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Prof. Dr. Klaus Schulten, University of Illinois at Urbana-Champaign

Prof. Dr. Klaus Schulten

April 15, 2014 3:35 pm | Biographies

Klaus Schulten is the leader in the field of computational biophysics, having devoted over 40 years to establishing the physical mechanisms underlying processes and organization in living systems from the atomic to the organism scale. Schulten is a strong proponent of the use of simulations as a "computational microscope", to augment experimental research

Understanding the Brain Site Features Funding Opportunities, Research across All Areas of Science

April 11, 2014 10:13 am | by NSF | News | Comments

On the first anniversary of President Obama's BRAIN Initiative announcement, the National Science Foundation (NSF) launched a new portal at NSF.gov/brain dedicated to the agency's brain research-related funding opportunities and news. The Web site also includes NSF's specific thematic research areas for the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative

DARPA Launches Biological Technologies Office

April 4, 2014 4:09 pm | by DARPA | News | Comments

A new DARPA technology office will merge biology, engineering and computer science to harness the power of natural systems for national security. Technology, like biology, constantly evolves. It is DARPA’s mission to stay ahead of the shifting technology curve by making critical, early investments in areas that cut across fields of research and enable revolutionary new capabilities for U.S. national security.

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Bigger than Big Data: The Key to Successful Translational Science

April 4, 2014 9:13 am | by Robin Munro, IDBS | Blogs | Comments

Is Big Data really the biggest challenge at the moment for translational science? Certainly there are issues with the complexity and size of omics data, which Big Data techniques can help address, but there are two more pressing challenges: enabling collaboration whilst facilitating information sharing, and the ability to better interpret multiple different omics data (multi-omics).

Computer Model Helps Breed Better Crops

April 3, 2014 3:52 pm | by University of Illinois at Urbana-Champaign | News | Comments

Crops that produce more while using less water seem like a dream for a world with a burgeoning population and already strained food and water resources. This dream is coming closer to reality for University of Illinois at Urbana-Champaign researchers who have developed a new computer model that can help plant scientists breed better soybean crops.

Turnip Rape with Pollinating Bumblebee and Caterpillar

April 2, 2014 2:48 pm | by University of Zurich | News | Comments

Flowering plants attract pollinating insects with scent from their flowers and bright colors. If they have become infested with herbivores like caterpillars, they attract beneficial insects like parasitic wasps with the help of scent signals from their leaves. The wasps then lay their eggs in the caterpillars and kill the parasites.

New Microscopy Technique Captures 3-D Cell Images Flowing through Microfluidic Channel

March 21, 2014 12:47 pm | by Anne Trafton, MIT | News | Comments

In 2007, MIT scientists developed a type of microscopy that allowed them to detail the interior of a living cell in three dimensions, without adding any fluorescent markers or other labels. This technique also revealed key properties, such as the cells’ density.

Computational Biophysicist Klaus Schulten to Speak on Large-Scale Computing in Biomedicine and Bioengineering

March 20, 2014 3:16 pm | by ISC | News | Comments

Dr. Klaus Schulten, a leading computational biophysicist and professor of physics at the University of Illinois at Urbana-Champaign will discuss “Large-Scale Computing in Biomedicine and Bioengineering” as the opening keynote address at the 2014 International Supercomputing Conference. ISC’14 will be held June 22-26 in Leipzig, Germany.

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Back from the Dead: Frozen for 1,600 years, Antarctic Moss Plant Revives

March 17, 2014 3:46 pm | by Seth Borenstein, AP Science Writer | News | Comments

Scientists have revived a moss plant that was frozen beneath the Antarctic ice and seemingly lifeless since the days of Attila the Hun. Dug up from Antarctica, the simple moss was about 1,600 years old, black and looked dead. But when it was thawed in a British lab's incubator, something happened. It grew again.

Klaus Schulten Talks about the Evolution of Computational Biophysics

March 14, 2014 10:26 am | by ISC | Articles | Comments

At this year's International Supercomputing Conference, Professor Klaus Schulten will deliver the opening keynote address on computing in biomedicine and bioengineering. Schulten, a physicist by training, now devotes his time to computation biophysics. He has contributed to several key discoveries in this area, has garnered numerous awards and honors for his work, and is considered one of preeminent leaders in field.

False-Color Image Highlights Earth’s Plant Growth

March 10, 2014 9:55 am | by Holli Riebeek, NASA | News | Comments

On August 3, 2004, NASA’s Mercury Surface, Space Environment, Geochemistry, and Ranging (MESSENGER) spacecraft began a seven-year journey, spiraling through the inner solar system to Mercury. One year after launch, the spacecraft zipped around Earth, getting an orbit correction from Earth’s gravity and getting a chance to test its instruments by observing its home planet.

High Performance Data Analysis: Big Data Meets HPC

March 7, 2014 3:33 pm | by Steve Conway, IDC | Blogs | Comments

From the start of the supercomputer era in the 1960s — and even earlier —an important subset of HPC jobs has involved analytics — attempts to uncover useful information and patterns in the data itself. Cryptography, one of the original scientific-technical computing applications, falls predominantly into this category.

Big Data Meets HPC

March 7, 2014 2:49 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Articles | Comments

Steve Conway, IDC VP HPC explains that, to date, most data-intensive HPC jobs in the government, academic and industrial sectors have involved the modeling and simulation of complex physical and quasi-physical systems. However, he notes that from the start of the supercomputer era in the 1960s — and even earlier — an important subset of HPC jobs has involved analytics, attempts to uncover useful information and patterns in the data itself.

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SciFinder Review: Chemistry/Biology References and More

March 6, 2014 4:31 pm | by John A. Wass, Ph.D. | Articles | Comments

This month’s review is a bit off of the usual track, e.g. statistical, mathematical and genomics software. However, it does include much pertinent information for chemists, chemical engineers and biologists. SciFinder is a search engine for chemistry and biology references for just about anything that can be accurately described in the search feature.

30,000-year-old Giant Virus found in Siberia

March 4, 2014 12:32 pm | News | Comments

A new type of giant virus called "Pithovirus" has been discovered in the frozen ground of extreme north-eastern Siberia. Buried underground, this giant virus, which is harmless to humans and animals, has survived being frozen for more than 30,000 years. It is the largest virus ever discovered.

NERSC Announces Second Annual HPC Achievement Awards

February 28, 2014 4:04 pm | by NERSC | News | Comments

The Department of Energy’s National Energy Research Scientific Computing Center (NERSC) announced the winners of its second annual High Performance Computing (HPC) Achievement Awards on February 4, 2014, during the annual NERSC User Group meeting at Lawrence Berkeley National Laboratory (Berkeley Lab).

What’s the Hold-up? Stuck in Slime for a Billion Years

February 24, 2014 4:10 pm | by University of Tasmania | News | Comments

Researchers have revealed ancient conditions that almost ended life on Earth, using a new technique they developed to hunt for mineral deposits. The first life developed in the ancient oceans around 3.6 billion years ago, but then life remained as little more than a layer of slime for a billion years. Suddenly, 550 million years ago, evolution burst back into action. So, what was the hold-up during those ‘boring billion’ years?

Whole Genome Analysis: When Each Patient is a Big Data Problem

February 20, 2014 11:28 am | by University of Chicago Medical Center | News | Comments

Although the time and cost of sequencing an entire human genome has plummeted, analyzing the resulting three billion base pairs of genetic information from a single genome can take many months. However, a team working with Beagle, one of the world's fastest supercomputers devoted to life sciences, reports that genome analysis can be radically accelerated. This computer is able to analyze 240 full genomes in about two days.

Systems Docking Simulation Algorithms Help Speed Drug Discovery

February 20, 2014 6:50 am | by Okinawa Institute of Science and Technology - OIST | News | Comments

A large number of neglected diseases exist in which each disease has only a small number of patients in the world, yet the number is still significant. Kun-Yi Hsin  is working on precisely this problem. In a recent article, he describes his work identifying potential drugs and targets for those drugs using a computational approach that has the potential to bring the cost of drug development down while increasing the speed of drug discovery.

Registration Opens for $2 Million Ocean Health XPRIZE

February 12, 2014 12:54 pm | by XPRIZE | News | Comments

XPRIZE has announced that team registration is open for the $2 million Wendy Schmidt Ocean Health XPRIZE, a competition to incentivize breakthroughs in ocean pH sensor technology that will radically transform our understanding of ocean acidification. Teams are expected to come from diverse backgrounds, ranging from nanotechnology and biotechnology to industrial chemistry and marine science

Statistical Mechanics, Mathematical Modeling Shed Light on Biological Memories

February 10, 2014 5:04 pm | by Lawrence Livermore National Laboratory | News | Comments

A Lawrence Livermore National Laboratory physicist and his colleagues have found a new application for the tools and mathematics typically used in physics to help solve problems in biology. Specifically, the team used statistical mechanics and mathematical modeling to shed light on something known as epigenetic memory — how an organism can create a biological memory of some variable condition, such as quality of nutrition or temperature.

ScienceCloud by Accelrys

February 7, 2014 10:39 am | Accelrys | Product Releases | Comments

ScienceCloud is an SaaS-based information management and collaboration workspace for externalized life science research and development. It is designed to advance collaborative drug discovery with a new generation of integrated applications built on a scalable, cloud-based scientific platform.

A New Frontier: Biologics ELN

February 7, 2014 8:52 am | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments

The rapid increase of investment in biotherapeutics is changing the profile of the biopharmaceutical industry and, along with it, data management in the laboratory. With attention on longer patent life, high barriers to generic equivalents and personalized medicine, an increasing portion of R&D spending is being allocated to large molecule therapies, such as monoclonal antibodies.

Robots with Insect Brains: Learning to Navigate Guided by External Stimuli

February 4, 2014 5:32 am | by Freie Universitaet Berlin | News | Comments

Researchers of Freie Universität Berlin, of the Bernstein Fokus Neuronal Basis of Learning, and of the Bernstein Center Berlin and have developed a robot that perceives environmental stimuli and learns to react to them. The scientists used the relatively simple nervous system of the honeybee as a model for its working principles. To this end, they installed a camera on a small robotic vehicle and connected it to a computer.

NERSC Flips Switch on New Flagship Supercomputer, Edison

January 31, 2014 2:21 pm | by Margie Wylie, Berkeley Lab | News | Comments

The National Energy Research Scientific Computing (NERSC) Center recently accepted “Edison,” a new flagship supercomputer designed for scientific productivity. Named in honor of American inventor Thomas Alva Edison, the Cray XC30 will be dedicated in a ceremony held at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) on February 5, 2014, and scientists are already reporting results.

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