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At their heart, the simulations are akin to modeling chemical reactions taking place between different elements and, in this case, we have four states a person can be in — human, infected, zombie or dead zombie — with approximately 300 million people. Cou

Statistical Mechanics Reveal Ideal Hideout to Save your Brains from the Undead

March 2, 2015 2:26 pm | by American Physical Society | News | Comments

Researchers focusing on a fictional zombie outbreak as an approach to disease modeling suggest heading for the hills, in the Rockies, to save your brains from the undead. Reading World War Z: An Oral History of the First Zombie War, and taking a graduate statistical mechanics class inspired a group of Cornell University researchers to explore how an "actual" zombie outbreak might play out in the U.S.

Logic-defying Mathematical Model could lead to Better Skin Grafts, New Smart Materials

February 26, 2015 2:00 pm | by Cassi Camilleri, University of Malta | News | Comments

Pull on a piece of plastic at separate ends; it becomes thinner. So does a rubber band. One...

Three Men First to Get Reconstructed Bionic Hands

February 26, 2015 1:18 pm | by Maria Cheng, AP Medical Writer | News | Comments

Three Austrians have replaced injured hands with bionic ones that they can control using nerves...

Novel 3-D Computer Model brings Insight to Cardiovascular Diseases

February 26, 2015 12:56 pm | by Lappeenranta University of Technology, LUT | News | Comments

Researchers have developed a novel three-dimensional, multiscale and multicomponent model of the...

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Scientists at the University of Valencia have developed a research methodology called Anatomical Network Analysis (AnNA), based on network analysis mathematical tools for studying anatomy. Courtesy of Asociación RUVID

Modular Anatomical Structure of Human Head Described for First Time

February 18, 2015 10:03 am | by Asociación RUVID | News | Comments

A new mathematical analysis tool has allowed a deeper understanding of the anatomy of the human head, describing the skull as an extended network structured in 10 modules. Researchers have developed a research methodology called Anatomical Network Analysis (AnNA), based on network analysis mathematical tools for studying anatomy.

Omics Explorer 3.1 Advanced Data Analysis Software

Omics Explorer 3.1 Advanced Data Analysis Software

February 12, 2015 1:32 pm | Qlucore AB | Product Releases | Comments

Qlucore Omics Explorer 3.1 advanced data analysis software features a well-defined open interface to R. The interface allows users to utilize a broad range of statistical tests, to use existing tests in R, and to write new ones. The inbuilt statistical functions of the bioinformatics program are extended with the R interface to include the full suite of statistical methods available in R.

Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source

Helping to Save Lives of Critically Ill Children

February 12, 2015 10:17 am | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Articles | Comments

For those on the front lines of treating cancer, speed and precision are key to patients’ survival. Pediatric cancer researchers have been making incredible strides in accelerating delivery of new diagnostic and treatment options. Supercomputer-powered genetic diagnosis is being used to harness the power of high throughput genomic and proteomic methods and is playing a key role in improving the outcome for children with genetic diseases.

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Map generated by more than 250 million public tweets Courtesy of Salathé et al.

Digital Disease Detection: Using Big Data to Detect Outbreaks

February 10, 2015 11:42 am | by PLOS | News | Comments

Personal information taken from social media, blogs, page views and so on is used to detect disease outbreaks, but does this violate our privacy, consent and trust? Dr. Effy Vayena from the University of Zurich and colleagues have mapped the numerous ethical challenges confronting digital disease detection and propose a framework to address the questions.

John Wass is a statistician based in Chicago, IL.

Explorations of Mathematical Models in Biology with Maple

February 10, 2015 9:29 am | by John A. Wass, Ph.D. | Articles | Comments

The author of this wonderful text delivers a brief, easy-to-absorb, yet very comprehensive text on modeling real-world data with Maple. Maple is software for performing mathematics, with a none-too-steep learning curve. In the introduction, the author is quick to point out that this is neither a detailed textbook of mathematical modeling, nor Maple. It is, however, a very well-written manual of introductory modeling and use of Maple.

ENIGMA cipher machine  Rotor Set Courtesy of Andy L.

Similar Statistics Play Role in Decision Making and World War II Code Breaking

February 9, 2015 11:22 am | by Cell Press | News | Comments

Statistical decision making resembles a process Alan Turning's team did in Bletchley Park to work out the settings of German enigma machines. In order to make use of the large clicking machine, Turing's team analyzed pairs of randomly intercepted German messages, aligned them one above the other to accumulate evidence from letter pairs until they reach a threshold level of certainty that the messages were sent on identical enigma machine.

Heatmap of the Pseudomonas genus, the most abundant genus found across the city. Hotspots are found in areas of high station density and traffic (i.e. lower Manhattan and parts of Brooklyn). Courtesy of Ebrahim Afshinnekoo

Researchers Produce 1st Map of NYC Subway System Microbes

February 9, 2015 10:52 am | by Weill Cornell Medical College | News | Comments

The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague. A pathogen map of a city provides a baseline assessment. Repeated sampling could be used for long-term, accurate disease surveillance, bioterrorism threat mitigation, and large-scale health management.

Smartphone dongles performed a point-of-care HIV and syphilis test in Rwanda from finger prick whole blood in 15 minutes, operated by health care workers trained on a software app. Courtesy of Samiksha Nayak, Columbia Engineering

Smartphone, Finger Prick, 15 Minutes — Diagnosis!

February 6, 2015 3:20 pm | by Holly Evarts, Columbia University | News | Comments

A team of researchers has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three HIV and syphilis infectious disease markers from a finger prick of blood in just 15 minutes. The device replicates, for the first time, all mechanical, optical and electronic functions of a lab-based blood test. Specifically, it performs an ELISA assay.

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Brain Researcher Marianne Fyhn receives computation help from, among others, Gaute Einevoll and Anders Malthe-Sørenssen to acquire an understanding of how the brain Works.

Mathematics to Reveal Secrets of the Brain

February 5, 2015 4:33 pm | by Yngve Vogt, University of Oslo | News | Comments

Top researchers are using mathematical modelling and heavy computations to understand how the brain can both remember and learn. Ten years ago, when the team of Marianne Fyhn and Torkel Hafting Fyhn cooperated with the Nobel Prize winning team of May-Britt and Edvard Moser at NTNU, they discovered the sense of orientation in the brain.

Researchers found that the link between having a faster-running biological clock and early death held true even after accounting for other factors such as smoking, diabetes and cardiovascular disease. Courtesy of Elliott Brown

DNA Clock Helps Predict Individual Lifespans

February 5, 2015 4:14 pm | by University of Edinburgh | News | Comments

Scientists have identified a biological clock that provides vital clues about how long a person is likely to live. Researchers studied chemical changes to DNA that take place over a lifetime, and can help them predict an individual's age. By comparing individuals’ actual ages with their predicted biological clock age, scientists saw a pattern emerging.

Microscopic image of senile plaques seen in the cerebral cortex of a person with Alzheimer's disease of presenile onset. Courtesy of KGH

Blue Waters Project helps Uncover Alzheimer's Complex Genetic Networks

February 5, 2015 4:06 pm | by NSF | News | Comments

The release of the film, Still Alice, in September 2014 placed a much-needed light on Alzheimer's disease, a debilitating neurological disease that affects a growing number of Americans each year. More than 5.2 million people in the U.S. are currently living with Alzheimer's. One out of nine Americans over 65 has Alzheimer's, and one out of three over 85 has the disease. For those over 65, it is the fifth leading cause of death.

In the United States, big data environments are utilizing advanced computing systems to map phenotype to underlying process and to compare those who develop disease with those who don’t. To accomplish this, the researchers are assembling publically availa

Reversing the Global Diabesity Epidemic

February 5, 2015 2:38 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments

Diabesity has been identified as a major global health problem by researchers and healthcare professionals world-wide, including England’s National Health Service, Brigham and Women’s Hospital and Harvard Medical School, Ain Shams University Hospital in Cairo, Egypt, and a research consortium of the European Union.

American leafminer moth Coptodisca lucifluella has been invading Italian walnut orchards since 2010. Interestingly, the moth lives on pecan trees in the United States, but invaded a new host plant in Europe: the walnut tree.

Leafminer Moth Invades Italy

February 3, 2015 4:14 pm | News | Comments

American leafminer moth Coptodisca lucifluella has been invading Italian walnut orchards since 2010. Interestingly, the moth lives on pecan trees in the United States, but invaded a new host plant in Europe: the walnut tree.       

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“In nanomedicine we need to understand physical phenomena on a nano scale, forming as correct a picture as possible of molecular phenomena. In this context, quantum chemical calculations are important,” says Michele Cascella. Courtesy of Hanne Utigard

Quantum Chemistry Closing in on Quantum Mechanics of Living Cells

January 30, 2015 11:19 am | by Yngve Vogt, University of Oslo | News | Comments

Quantum chemical calculations have been used to solve big mysteries in space. Soon the same calculations may be used to produce tomorrow’s cancer drugs. Quantum chemical calculations are needed to explain what happens to the electrons’ trajectories within a molecule, and the results of a quantum chemical calculation are often more accurate than what is achievable experimentally.

ACD/Labs 2015 Cheminformatics Software

ACD/Labs 2015 Cheminformatics Software

January 29, 2015 10:38 am | Advanced Chemistry Development, Inc. | Product Releases | Comments

ACD/Labs 2015 cheminformatics software builds upon the capabilities of the ACD/Spectrus and ACD/Percepta platforms. The ACD/Spectrus Platform is designed to make it easier for organizations to handle unified analytical data from multiple techniques and instruments. The ACD/Percepta Platform features improvements in the speed of calculation of physicochemical and ADME-Tox properties and expanded capabilities to leverage organizational knowledge.

Production of growth factors (IGF-II) as public goods game network: this microscopic image shows how cancer cells (colorless cells) that do not produce IGF-II but need it for their growth reproduce in a population of cancer cells that produces and consume

Game Theory Explains Social Interactions of Cancer Cells

January 28, 2015 2:33 pm | by University of Basel | News | Comments

Researchers were able to predict the interactions of cancer cells using a part of game theory known as the public goods game, suggesting that work on the social interactions among cancer cells may provide insight into the dynamics of cancer. Researchers applied this model to the cooperation between producing and non-producing members of a cancer cell population, in order to examine if the model is also applicable to biological processes.

The Biosurveillance Gateway site offers a variety of Los Alamos-developed biosurveillance tools that can be used for decision support in disease surveillance.

Biosurveillance Gateway Supports Centralized Global Disease Response

January 28, 2015 2:21 pm | by Los Alamos National Laboratory | News | Comments

A new online resource, called the Biosurveillance Gateway, is in place at Los Alamos National Laboratory, providing a centralized portal for all news, information, resources and research related to biosurveillance at the laboratory. The goal of the site is to support global disease surveillance, providing useful tools for professionals around the world to reference from a single location.

Clemson University associate professor of genetics and biochemistry Alex Feltus is co-principal investigator on the Tripal Gateway project award.

Researchers get $1.4 Million to Advance Big Data for Genomic Research

January 22, 2015 2:04 pm | by Brian M. Mullen, Clemson University | News | Comments

A team of scientists has received a $1.4 million grant from the National Science Foundation to help meet the growing needs of the data-driven genomic science community. The Tripal Gateway project will build on existing cyberinfrastructure to enhance the capacity of genomic databases to manage, exchange and process “big data.”

An international team of roughly 300 scientists pooled brain scans and genetic data worldwide to pinpoint genes that enhance or break down key brain regions in people from 33 countries. This is the first high-profile study since the NIH launched its Big D

Global Consortium Cracks Part of Brain’s Genetic Code

January 21, 2015 4:05 pm | by Alison Trinidad, Keck Medicine of USC | News | Comments

In the largest collaborative study of the brain to date, researchers from the Keck School of Medicine of the University of Southern California (USC) led a global consortium of 190 institutions to identify eight common genetic mutations that appear to age the brain an average of three years. The discovery could lead to targeted therapies and interventions for Alzheimer’s disease, autism and other neurological conditions.

Biomolecule Toolkit

Biomolecule Toolkit

January 21, 2015 12:27 pm | ChemAxon, Ltd. | Product Releases | Comments

The Biomolecule Toolkit is a Web service-based toolkit designed to bridge the gap between biology and chemistry for complex biomolecular entities. It provides unambiguous representation at the sequence and atomic level for a diverse set of biomolecules such as peptides, oligonucleotides, proteins and antibody drug conjugates, including those containing unnatural and chemically-modified components, thereby allowing their storage, indexing and search within a database.

Solar panels on the roof of the Paul VI Hall, at the Vatican. Pope Benedict XVI was dubbed "the Green Pope" for his frequent calls to stop ecological devastation and his efforts to bring solar power to the Vatican city-state. "Can we remain indifferent be

Pope's Statement on Climate Change: 5 Things to Know

January 20, 2015 2:43 pm | by Rachel Zoll, AP Religion Writer | News | Comments

Pope Francis, who pledged on the day of his installation as pontiff to make the environment a priority, is drafting a highly anticipated encyclical on ecology and climate change. Environmentalists are thrilled by the prospect of a rock-star pope putting his moral weight behind efforts to curb global warming. Francis said he wanted the document to be released in time to be read before the next round of U.N. climate treaty talks in Paris.

This live panel discussion looks at how big data and data science have fast become the next frontier for innovation, competition and productivity.

Big Data Insights: Accelerating Discovery in Medicine, Research & More

January 20, 2015 11:51 am | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments

On Wednesday, January 21, Scientific Computing will host a live panel discussion that looks at how big data and data science have fast become the next frontier for innovation, competition and productivity. One of today’s significant advances in data science introduces us to the Next Generation Cyber Capability (NGCC) at Arizona State University (ASU)...

William Weaver is an associate professor in the Department of Integrated Science, Business, and Technology at La Salle University.

By Any Other Name: The Central Role of Informatics in STEM Education

January 9, 2015 3:05 pm | by William Weaver, Ph.D. | Blogs | Comments

The human lament that things in the past were much simpler is an accurate observation made from the perspective of riding along an exponentially increasing complexity curve. Examining the present or looking into the future can be a confusing torrent of concepts, vocabulary and technologies that appear to be spiraling out-of-control. At the First IEEE Integrated STEM Education Conference, Professor Steve Zilora reflected on this increase...

 Using a new algorithm ECG map can help diagnose the location of cardiac disorder in a way which is better for the patients and more cost effective for health services. Courtesy of Meul

Electrocardiogram Algorithm Pinpoints exact Location of Heart Defects

January 8, 2015 3:15 pm | by Manchester University | News | Comments

A new technique to help surgeons find the exact location of heart defects could save lives, help them to treat patients more effectively and save health service cash. The development will allow non-invasive detection of the origin of heart problems and allow more effective treatment.

A bundle of nerves that relays information from touch receptors on the skin to the spinal cord and ultimately the brain, imaged with the new technique. Courtesy of EMBL/L.Castaldi -- Click to enlarge

Unprecedentedly Detailed Image of Mouse Neurons

January 7, 2015 12:48 pm | by European Molecular Biology Laboratory | News | Comments

Scientists can now explore nerves in mice in much greater detail than ever before, thanks to an approach developed by scientists at the European Molecular Biology Laboratory. The work enables researchers to easily use artificial tags, broadening the range of what they can study and vastly increasing image resolution.

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