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This protein model represents an NMDA receptor, which juts halfway out of the surface of cells of the nervous system that include the brain and spinal cord. It relays signals between nerve cells. Researchers found that a mechanical coupling was needed bet

Stampede used to Perform Modeling to Advance Potential Drug Targets for Alzheimer's, Parkinson's, Schizophrenia

September 23, 2014 3:59 pm | by Jorge Salazar, TACC | News | Comments

It all begins in the brain as a flood, tens of millions of neurotransmitters handed off from one neuron to another in just a fraction of a second. Memories, dreams and learning share a common thread in this exchange of electrical and chemical signals by the nearly 100 billion spindly neurons of the brain, each cell networked to 10,000 others.

Math Model Replaces Invasive Kidney Biopsy for Lupus Patients

September 18, 2014 2:11 pm | by Emily Caldwell, Ohio State University | News | Comments

Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney...

Martian Meteorite Yields More Evidence of the Possibility of Life on Mars

September 18, 2014 2:05 pm | by University of Manchester | News | Comments

A tiny fragment of Martian meteorite 1.3 billion years old is helping to make the case for the...

StarDrop 5.5 Software Suite

September 16, 2014 3:15 pm | Product Releases | Comments

StarDrop 5.5 is a suite of software for guiding decisions in drug discovery, helping project...

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Associate Professor Federico Lauro (left) and his wife Rachelle Jensen holding a sample cartridge

Building a Global Network of Citizen Oceanographers

September 12, 2014 3:00 pm | by Nanyang Technological University (NTU) | News | Comments

NTU is working with other international universities to build a global network of ‘citizen scientists’ on a free-to-access database for oceanographic data. To gain a better understanding of marine microbes that support the nutrient cycle and form the foundation of the food web, NTU scientists have embarked on a pilot project to crowd-source the collection of oceanographic data globally.

Initial research focused on optimization of the PMEMD classical molecular dynamics code, part of the widely used AMBER Molecular Dynamics software, on multi-core Intel Xeon processors and “manycore” Intel Xeon Phi processors.

SDSC Joins Intel Parallel Computing Centers Program with Focus on Molecular Dynamics, Neuroscience and Life Sciences

September 12, 2014 2:44 pm | by San Diego Supercomputer Center | News | Comments

The San Diego Supercomputer Center (SDSC) at the University of California, San Diego, is working with semiconductor chipmaker Intel to further optimize research software to improve the parallelism, efficiency, and scalability of widely used molecular and neurological simulation technologies.

Parents and physicians and scientists from the Neuroblastoma and Medulloblastoma Translational Research Consortium and TGen have teamed to launch a groundbreaking personalized medicine clinical trial investigation for pediatric cancer.

Providing Critical Child-cancer Research Tools to Speed Development of Personalized Treatments

September 11, 2014 3:25 pm | by TGen | News | Comments

Dell, Terascala and the Translational Genomics Research Institute are installing state-of-the-art computing and programing specialized for human genome investigations at the National Cancer Institute. The mission of the Oncogenomics Section at the NCI is to harness the power of high throughput genomic and proteomic methods to improve the outcome of children with high-risk metastatic, refractory and recurrent cancers.

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Ralph Lauren Corp. is unveiling the high-performance, fashion-forward Polo Tech shirt on opening day of the US Open. The Polo Tech shirt is an innovative new product from a fashion brand that merges biometrics into active lifestyle apparel, marking a revo

Ralph Lauren Introduces the Next Evolution of Wearable Technology

September 3, 2014 3:33 pm | by Ralph Lauren Corporation | News | Comments

Ralph Lauren Corp. is unveiling the high-performance, fashion-forward Polo Tech shirt on opening day of the US Open. The Polo Tech shirt is an innovative new product from a fashion brand that merges biometrics into active lifestyle apparel, marking a revolution in advanced technology designed to improve general wellness and increase personal fitness.

The industry's preeminent event on Molecular Medicine, focusing on Drug Discovery, Genomics, Diagnostics and Information Technology.

22nd International Molecular Medicine Tri-Conference

August 28, 2014 3:17 pm | Events

The 22nd International Molecular Medicine Tri-Conference is the industry's Preeminent Event on Molecular Medicine, focusing on Drug Discovery, Genomics, Diagnostics and Information Technology. Spanning six days this year, the Tri-Conference includes an expanded program that includes 6 symposia, over 20 short courses, and 17 conference programs.

The Expo provides the perfect venue to share information and discuss enabling technologies that are driving biomedical research and the drug development process

2015 Bio-IT World Conference & Expo

August 28, 2014 3:06 pm | Events

The 2015 Bio-IT World Conference & Expo plans to unite 3,000+ life sciences, pharmaceutical, clinical, healthcare, and IT professionals from 32+ countries. The Expo provides the perfect venue to share information and discuss enabling technologies that are driving biomedical research and the drug development process.

Pathogenic bacteria (red) live side-by-side with benign species (green) in a healthy mouth. Scientists are beginning to understand what causes bacterial communities to shift from health to diseases like periodontitis, diabetes, and Crohn's disease. Courte

Mouth Bacteria Can Change its Diet, Supercomputers Reveal

August 22, 2014 12:28 pm | by Jorge Salazar, TACC | News | Comments

Bacteria inside your mouth drastically change how they act when you're diseased. Scientists say these surprising findings might lead to better ways to prevent or even reverse the gum disease periodontitis, diabetes and Crohn's disease. UT Austin researchers used shotgun metagenomic sequencing, a non-targeted way to study the all the genetic material of the bacterial communities. They analyzed the RNA collected with  Lonestar and Stampede.

The Ebola virus viewed through an electron microscope. As of mid-2014, Ebola has caused two dozen outbreaks in Africa since the virus first emerged in 1976. (AP Photo/Antwerp Institute of Tropical Medicine)

Another Ebola Problem: Finding its Natural Source

August 18, 2014 12:25 pm | by Mike Stobbe and Marilynn Marchione, AP Medical Writers | News | Comments

A scary problem lurks beyond the frenzied efforts to keep people from spreading Ebola: No one knows exactly where the virus comes from or how to stop it from seeding new outbreaks. Ebola has caused two dozen outbreaks in Africa since it first emerged in 1976. It is coming from somewhere — probably bats — but experts agree they need to pinpoint its origins in nature.

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Bain de Japonais Spring, an intertidal hydrothermal vent on Prony Bay. Courtesy of Roy Price, NASA

Our Ancestor’s Leaky Membrane answers Big Biology Questions

August 13, 2014 2:34 pm | by University College London | News | Comments

All life on Earth came from one common ancestor — a single-celled organism — but what it looked like, how it lived, and how it evolved into today’s modern cells is a four-billion-year-old mystery being solved by researchers using mathematical modeling. Findings suggest for the first time that life’s Last Universal Common Ancestor (LUCA) had a ‘leaky’ membrane, which helps scientists answer two of biology’s biggest questions...

An April memo from the EPA's chief of staff said that "unsolicited contacts" need to be "appropriately managed" and that committee members should refrain from directly responding to requests about committees' efforts to advise the agency.

Groups to EPA: Stop Muzzling Science Advisers

August 13, 2014 12:39 pm | by Dina Cappiello, Associated Press | News | Comments

Journalist and scientific organizations accused the EPA of attempting to muzzle its independent scientific advisers by directing them to funnel all outside requests for information through agency officials. In a letter on August 12, 2014, groups representing journalists and scientists urged the EPA to allow advisory board members to talk directly to news reporters, Congress and other outside groups without first asking for permission.

Seamlessly marrying electronics and brain signaling could transform how we treat some of the most puzzling and devastating diseases. Courtesy of Janulla

On the Frontiers of Cyborg Science: Seamless Marriage between Electronics and Brain Signaling

August 11, 2014 12:22 pm | by ACS | News | Comments

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits. Taking this human-machine concept to an unprecedented level, pioneering scientists are working on the seamless marriage between electronics and brain signaling, with the potential to transform our understanding of how to treat the brain's most devastating diseases.

A close-up of tiny bioink droplets used to print organs shows live cells inside. Courtesy of the American Chemical Society

Exploring 3-D Printing to Make Organs for Transplants

July 30, 2014 9:44 am | by American Chemical Society | News | Comments

Printing whole new organs for transplants sounds like something out of a sci-fi movie, but the real-life budding technology could one day make actual kidneys, livers, hearts and other organs for patients who desperately need them. In the ACS journal Langmuir, scientists are reporting new understanding about the dynamics of 3-D bioprinting that takes them a step closer to realizing their goal of making working tissues and organs on-demand.

ArxLab Notebook Web-based Electronic Notebook

ArxLab Notebook Web-based Electronic Notebook

July 29, 2014 3:15 pm | by Arxspan | Product Releases | Comments

ArxLab Notebook is a Web-based electronic notebook application. Its SaaS platform is intended for use in experimental sciences; it is preconfigured for chemistry and biology workflows while supporting free-form research notes and data. The software provides full audit trails, electronic signatures, witnessing workflows and built-in sharing functionality.

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Computer Models Reveal Quantum Effects in Biological Oxygen Transport

July 18, 2014 3:41 pm | by Trinity College | News | Comments

Physicists have created a unique combination of computer models, based on the theory of quantum mechanics, and applied them to a previously well-characterized protein found in muscle to develop a new picture of how biomolecules transport and store oxygen (O2). In doing so, the team has shown how the process of respiration, which is fundamental in humans and other vertebrates, exploits quantum mechanical effects working on tiny scales.

Vampire Bat Venom Could Hold Key to New Drugs for Stroke, High Blood Pressure

July 15, 2014 4:38 pm | by University of Queensland | News | Comments

An international team of scientists has discovered that vampire bat venom contains molecules capable of evading the victim’s immune system. The results point to entirely new forms of anticoagulants in the venom, as well as novel molecules that cause dilation of the small arteries near the skin.

Brain Cancer Stem Cells from Human Brain Cancer Tissue

July 11, 2014 12:23 pm | News | Comments

This 200x photo of brain cancer stem cells from human brain cancer tissue received an Image of Distinction designation in the 2013 Nikon Small World Photomicrophotography Competition, which recognizes excellence in photography with the optical microscope. It was taken using immunofluorescence.

SLAS2015

July 11, 2014 10:24 am | by SLAS | Events

SLAS is a global organization that provides forums for education and information exchange to encourage study and professional collaboration aimed at advancing laboratory science and technology for the drug discovery, biotechnology, chemical, data informatics, clinical diagnostic, consumer product, pharmaceutical, and other industries.

Pittcon 2015 Technical Program Places Emphasis on Energy and Fuels

July 8, 2014 4:05 pm | by Pittcon | News | Comments

The Program Committee has announced a call for papers for the Pittcon 2015 Technical Program.  Abstracts are currently being accepted for contributed oral and poster presentations in areas such as, but not limited to, analytical chemistry, applied spectroscopy, life science, bioanalysis, food science, nanotechnology, environmental science and pharmaceutical. The 2015 committee is especially interested in topics relevant to energy and fuels.

Statistical Analysis Could Improve Understanding and Treatment of Different Brain Tumors

July 7, 2014 10:21 am | by Qlucore | News | Comments

Discovering a brain tumor is a very serious issue, but it is not the end of the story. There are many different types of brain tumor with different survival rates and different methods for treatment. However, today, many brain tumors are difficult to clearly diagnose, leading to poor prognoses for patients.

Muscle-powered Bio-bots Walk on Command

July 1, 2014 10:18 am | by University of Illinois | News | Comments

Engineers at the University of Illinois at Urbana-Champaign demonstrated a class of walking “bio-bots” powered by muscle cells and controlled with electrical pulses, giving researchers unprecedented command over their function.       

This 65x image shows an inner ear from a Claudin 11-null mouse revealing the distribution of tight junctions (blue).

Mouse Inner Ear

June 30, 2014 8:40 am | News | Comments

This 65x image shows an inner ear from a Claudin 11-null mouse revealing the distribution of tight junctions (blue). The brightfield photo taken by Dr. Alexander Gow and Cherie Southwood of Wayne State University, Department of Genetics, Detroit, Michigan received an Image of Distinction designation in the 2013 Nikon Small World Photomicrophotography Competition, which recognizes excellence in photography with the optical microscope.

Nerve agent sarin bound to bioscavenger enzyme

Chemical Weapons: Engineering Enzymes to Neutralize Nerve Agents

June 17, 2014 2:15 pm | by The University of Tennessee | News | Comments

Researchers at The University of Tennessee are a step closer to creating a prophylactic drug that would neutralize the deadly effects of the chemical weapons used in Syria and elsewhere. Jeremy Smith, UT-ORNL Governor’s Chair and an expert in computational biology, is part of the team that is trying to engineer enzymes — called bioscavengers — so they work more efficiently against chemical weapons. 

The quest to create artificial blood is big business, with the past 25 years seeing up to £2 billion invested globally on research into a usable alternative and many major US companies falling by the wayside in the hunt for a substitute.

The Quest for Blood: Finding a Long-lasting, One-size-fits-all Viable Substitute

June 12, 2014 3:47 pm | by University of Essex | News | Comments

Every day thousands of people around the world have their lives saved or improved thanks to someone giving blood. But imagine how many more lives could be saved if a long-lasting blood substitute could be found, which could easily be stored at room temperature and available to all patients, regardless of their blood type. This is the challenge a team of scientists at the University of Essex are hoping to overcome with their Haem02 project 

Mouse osteoblasts growing over 3D matrixes developed from food industry waste Courtesy of Milagros Ramos and Ana Martínez Serrano, CTB-UPM

Beer Brewing Waste could Help Bone Regeneration

June 9, 2014 2:38 pm | by Universidad Politécnica de Madrid | News | Comments

Researchers have developed biomaterials for bone regeneration from beer brewing waste. The waste obtained from the beer brewing process contains the main chemical components found in bones (phosphorus, calcium, magnesium and silica). After undergoing modification processes, this waste can be used as support or scaffold to promote bone regeneration for medical applications, such as coating prosthesis or bone grafts.

Swedish geochemist Alatariel Elensar submitted the idea for a female set featuring minifigure scientists — an astronomer with a telescope, a paleontologist with a dinosaur and a chemist in a lab.

New LEGO Set Celebrates Women in Science

June 5, 2014 10:10 am | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments

LEGO has announced that a female minifigure set, featuring three scientists along with their lab gear, will be released as the next LEGO Ideas set. This “Research Institute” model is an official set of all-female scientist figures — a paleontologist, an astronomer and a chemist — made with regular LEGO minifigures.

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