What do Rudolph Guliani, Robert Diniro, Dennis Hopper, James Brown, Arnold Palmer, Joe Torre, Dan Fogelberg, Colin Powell, John Kerry, Johnny Ramone, Francois Mitterand, Robert Frost, and Frank Zappa have in common? They have lived with, or died from, prostate cancer. Every 19 minutes, an American man dies from prostate cancer. It is the second leading cause of cancer death among men and is the most common cancer in men...
Paralyzed from the neck down after suffering a gunshot wound when he was 21, Erik G. Sorto now...
Anyone can suffer from an infection, for example in their stomach, urinary tract or skin....
MC10 is developing a technology that will allow digital circuits to be embedded in bendable,...
Advances in technology have generated vast amounts of “omics” data: genomic, epigenomic, transcriptomic, proteomic and metabolomic changes for all types of specimens. Bridging the gap between data generation and investigators’ ability to retrieve and interpret data is essential to realize the biological and clinical value of this wealth of information.
Researchers have mimicked the way the human brain processes information with the development of an electronic long-term memory cell, which mirrors the brain’s ability to simultaneously process and store multiple strands of information. The development brings them closer to imitating key electronic aspects of the human brain — a vital step toward creating a bionic brain and unlocking treatments for Alzheimer’s and Parkinson’s diseases.
A new initiative designed to advance how scientists digitally reconstruct and analyze individual neurons in the human brain will receive support from the supercomputing resources at the Department of Energy’s Oak Ridge National Laboratory (ORNL). Led by the Allen Institute for Brain Science, the BigNeuron project aims to create a common platform for analyzing the three-dimensional structure of neurons.
Computer simulation of the body’s inflammatory response to traumatic injury accurately replicated known individual outcomes and predicted population results. Researchers examined blood samples from 33 survivors of car or motorcycle accidents or falls for multiple markers of inflammation, including interleukin-6, and segregated the patients into categories of trauma severity. They were able to validate model predictions.
Today's LIMS allow research institutions to monitor and manage a broad array of biomedical research processes end-to-end and remotely. But how do they accommodate the ongoing flood of discoveries in areas such as genetics, the -omics, regenerative medicine and behavior, ongoing adjustments to workflows and protocols, tens of thousands of animals, and the evolution of legislative, welfare quality, and ethics directives?
IBM Watson is collaborating with more than a dozen leading cancer institutes to accelerate the ability of clinicians to identify and personalize treatment options for their patients. The institutes will apply Watson's advanced cognitive capabilities to reduce from weeks to minutes the ability to translate DNA insights, understand a person's genetic profile and gather relevant information from medical literature to personalize treatment.
Conventional silicon-based computing, which has advanced by leaps and bounds in recent decades, is pushing against its practical limits. DNA computing could help take the digital era to the next level. Scientists are now reporting progress toward that goal with the development of a novel DNA-based GPS.
Researchers studying how the brain makes decisions have, for the first time, recorded the moment-by-moment fluctuations in brain signals that occur when a monkey making free choices has a change of mind. The findings result from experiments led by electrical engineering Professor Krishna Shenoy, whose Stanford lab focuses on movement control and neural prostheses — such as artificial arms — controlled by the user's brain.
Just as the extraordinary capabilities of 3D printing have begun to infiltrate industry and the family home, researchers have started to develop 3D printed materials that morph into new structures post production, under the influence of external stimuli, such as water or heat — hence the name, 4D printing.
The GenomeStack Big Data Analytics platform has been developed specifically for bioinformatics researchers, data scientists and analysts conducting genome research. The database replaces the traditional file-based, manual process for storing and analyzing genome sequenced data.
Riedel-Kruse and his team are enabling people to interact with biological materials and perform experiments the way they interact with computers today — called interactive biotechnology. They have created three related projects that begin to define this new field. In the most far-reaching project, Riedel-Kruse created a robotic biology cloud lab capable of carrying out remote-control experiments.
Curtis writes algorithms that enable computers to solve large-scale continuous optimization problems. He is collaborating with researchers at Argonne through a five-year Early Career Award from the U.S. Department of Energy. In a three-year single-investigator project for the NSF, Curtis has developed algorithms that solve large-scale continuous optimization problems in less than a quarter of the time required by conventional methods.
All the computing power in the world isn’t useful if the software designed to access it is poorly designed. And we’re all much more discerning about user interfaces and usability: we expect our laboratory software to behave as intuitively as our smartphones. After all, laboratory employees are unlikely to be preoccupied with lines of codes and processors — they’re focused more on how easy the software is to use.
Study Combines Field Experiments, Predictive Modeling to Look at How Forests Worldwide Respond to Climate ChangeApril 7, 2015 5:09 pm | by Oak Ridge National Laboratory | News | Comments
Researchers from the Department of Energy’s Oak Ridge National Laboratory will play key roles in an expansive new project that aims to bring the future of tropical forests and the climate system into much clearer focus by coupling field research with the development of a new ecosystem model.
Researchers have long believed that supercomputers give universities a competitive edge in scientific research, but now they have some hard data showing it’s true. A Clemson University team found that universities with locally available supercomputers were more efficient in producing research in critical fields than universities that lacked supercomputers.
Legions of viruses that infect the leaves of tobacco plants could be the key to making power plants safer, heating and cooling buildings more efficient and “really kick-ass computers,” or to the liquid cooling of high-powered electronic devices, like radar systems. These tiny protein bundles, which were once a threat to a staple cash crop, are now helping researchers better understand the processes of boiling and condensation.
The decades worth of data collected about the billions of neurons in the brain is astounding. To help scientists make sense of this “brain big data,” researchers at Carnegie Mellon University have used data mining to create a publicly available Web site that acts like Wikipedia, indexing physiological information about neurons. The site will help to accelerate the advance of neuroscience research by providing a centralized resource.
A world-first collaboration uses previously top-secret technology to zoom through the human body down to the level of a single cell and could be a game-changer for medicine. UNSW Australia's Professor Tate is first to use the system in humans. She has forged a pioneering partnership with the US-based Cleveland Clinic, Brown and Stanford Universities, as well as Zeiss and Google to help crunch terabytes of data gathered from human study.
To a large degree, your brain is what makes you... you. It controls your thinking, problem solving and voluntary behaviors. At the same time, your brain helps regulate critical aspects of your physiology, such as your heart rate and breathing. And yet your brain — a nonstop multitasking marvel — runs on only about 20 watts of energy, the same wattage as an energy-saving light bulb.
Efficient, Time Sensitive Execution of Next-gen Sequencing Pipelines Critical for Translational MedicineApril 6, 2015 3:26 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments
Demand for genomics processing is rapidly spreading from research labs to the clinical arena. Genomics is now a "must have" tool for researchers in areas of oncology and rare diseases. It is also becoming a requirement in the clinical space for precision medicine, translational medicine and similar "bench to bedside" initiatives.
Researchers have created an algorithm that allowed a man to grasp a bottle with a prosthetic hand powered only by his thoughts. The technique, demonstrated with a man whose right hand had been amputated, uses non-invasive brain monitoring, capturing brain activity to determine what parts of the brain are involved in grasping an object. A computer program, or brain-machine interface (BMI), harnessed the subject’s intentions...
Researchers studying cancer and other invasive diseases rely on high-resolution imaging to see tumors and other activity deep within the body's tissues. Using photoacoustic microscopy, a single-wavelength, pulse-width-based technique, they were able to see blood flow, blood oxygenation, oxygen metabolism and other functions inside a living mouse brain at faster rates than ever before.
Researchers have developed a new computational model that effectively simulates the mechanical behavior of biofilms. Their model may lead to new strategies for studying a range of issues from blood clots to waste treatment systems. The new model may be adapted to study clot formation in blood vessels, which can pose the risk of detaching and migrating to the lungs, a fatal event.
Qlucore Omics Explorer 3.1 for Mac is data analysis software designed to maximize the outcome of research by making it easy to analyze experiment data from a biological point-of-view. Examples of this are the inbuilt Gene Ontology (GO) Browser, a Gene Set Enrichment Analysis (GSEA) function, and freedom to explore data using any variable identifier: variable collapse.
A new study suggests that a novel DNA-peptide structure can be used to produce thin, transparent and flexible screens. The research harnesses bionanotechnology to emit a full range of colors in one pliable pixel layer — as opposed to the several rigid layers that constitute today's screens.
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