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A carbapenem molecule, a last resort antibiotic, enters the carbapenemase enzyme (blue arrow), where the crucial beta-lactam structure gets broken down. The ineffective molecule then leaves (orange arrow)

Nobel Prize-winning Technique Helps Design Antibiotics of Future

October 17, 2014 11:52 am | by Bristol University | News | Comments

Scientists have used computer simulations to show how bacteria are able to destroy antibiotics — a breakthrough that will help develop drugs which can effectively tackle infections in the future. Researchers at the University of Bristol focused on the role of enzymes in the bacteria, which split the structure of the antibiotic and stop it from working, making the bacteria resistant.

Smithsonian Honors Founder of Virtual Reality Firm Oculus

October 17, 2014 11:03 am | by AP | News | Comments

The founder of virtual reality firm Oculus and singer Rosanne Cash and are among those who were...

Novel NIH Program will Create Database of Human Brain Cell Activity

October 10, 2014 12:08 pm | by UC Irvine | News | Comments

UC Irvine will receive $8 million from the NIH to establish one of six national centers...

Americans, German Awarded 2014 Nobel Prize in Chemistry

October 8, 2014 9:43 am | by Royal Swedish Academy of Sciences | News | Comments

The Royal Swedish Academy of Sciences has awarded the Nobel Prize in Chemistry to Eric Betzig of...

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The big-headed ant (Pheidole megacephala) is considered one of the world’s worst invasive ant species. Their giant, muscle-bound noggins power their biting parts, the mandibles, which they use to attack other ants and cut up prey. In a new study, research

Big-headed Ants Grow Bigger when Faced with Fierce Competitors

October 2, 2014 4:26 pm | by Diana Yates, University of Illinois | News | Comments

The big-headed ant (Pheidole megacephala) is considered one of the world’s worst invasive ant species. Their giant, muscle-bound noggins power their biting parts, the mandibles, which they use to attack other ants and cut up prey. In a new study, researchers report that big-headed ant colonies produce larger soldiers when they encounter other ants that know how to fight back.

Researchers have brought ultra-fast, nano-scale data storage within striking reach, using technology that mimics the human brain. They have built a novel nano-structure that offers a new platform for the development of highly stable and reliable nanoscale

Nano-scale Data Storage Mimics Brain Cells to Boost Memory Power

October 1, 2014 3:56 pm | by RMIT University | News | Comments

Researchers have brought ultra-fast, nano-scale data storage within striking reach, using technology that mimics the human brain. They have built a novel nano-structure that offers a new platform for the development of highly stable and reliable nanoscale memory devices.

An illustration of water in our Solar System through time from before the Sun’s birth through the creation of the planets. Courtesy of Bill Saxton, NSF/AUI/NRAO

Earth’s Water is Older than the Sun

September 25, 2014 4:00 pm | by Carnegie Institution of Washington | News | Comments

Water was crucial to the rise of life on Earth and is also important to evaluating the possibility of life on other planets. Identifying the original source of Earth’s water is key to understanding how life-fostering environments come into being and how likely they are to be found elsewhere. New work has found that much of our Solar System’s water likely originated as ices that formed in interstellar space.

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Bernie Spang is Vice President of Software Defined Strategy at IBM.

Scientific Research and Big Data: It Starts with Storage

September 24, 2014 11:52 am | by Bernie Spang, IBM | Blogs | Comments

For centuries, scientific research has been about data, and as data in research continues to grow exponentially, so does the importance of how it’s stored. A key example of how the scientific field can tackle Big Data storage is DESY, a scientific research organization dedicated to providing scientists worldwide faster access to insights into samples, making optimal data management in a high-volume environment extremely critical.

This protein model represents an NMDA receptor, which juts halfway out of the surface of cells of the nervous system that include the brain and spinal cord. It relays signals between nerve cells. Researchers found that a mechanical coupling was needed bet

Stampede used to Perform Modeling to Advance Potential Drug Targets for Alzheimer's, Parkinson's, Schizophrenia

September 23, 2014 3:59 pm | by Jorge Salazar, TACC | News | Comments

It all begins in the brain as a flood, tens of millions of neurotransmitters handed off from one neuron to another in just a fraction of a second. Memories, dreams and learning share a common thread in this exchange of electrical and chemical signals by the nearly 100 billion spindly neurons of the brain, each cell networked to 10,000 others.

Researchers have developed a math model that can predict the progression from nephritis — kidney inflammation — to interstitial fibrosis, scarring in the kidney that current treatments cannot reverse. Courtesy of Piotr Michał Jaworski

Math Model Replaces Invasive Kidney Biopsy for Lupus Patients

September 18, 2014 2:11 pm | by Emily Caldwell, Ohio State University | News | Comments

Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. Researchers have developed a math model that can predict the progression from kidney inflammation to scarring in the kidney that current treatments cannot reverse.

Is there life on Mars? Researchers say that life as we know it, in the form of bacteria, for example, could be there, although we haven’t found it yet. Courtesy of NASA/JPL/MSSS

Martian Meteorite Yields More Evidence of the Possibility of Life on Mars

September 18, 2014 2:05 pm | by University of Manchester | News | Comments

A tiny fragment of Martian meteorite 1.3 billion years old is helping to make the case for the possibility of life on Mars, say scientists. The finding of a ‘cell-like’ structure, which investigators now know once held water, came about as a result of collaboration between scientists in the UK and Greece. These findings are significant because they add to increasing evidence that Mars does provide all the conditions for life to have formed.

StarDrop 5.5 Software Suite

StarDrop 5.5 Software Suite

September 16, 2014 3:15 pm | Optibrium Ltd. | Product Releases | Comments

StarDrop 5.5 is a suite of software for guiding decisions in drug discovery, helping project teams quickly identify high-quality compounds. It works by evaluating complex data, which is often uncertain because of experimental variability or predictive error.

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Associate Professor Federico Lauro (left) and his wife Rachelle Jensen holding a sample cartridge

Building a Global Network of Citizen Oceanographers

September 12, 2014 3:00 pm | by Nanyang Technological University (NTU) | News | Comments

NTU is working with other international universities to build a global network of ‘citizen scientists’ on a free-to-access database for oceanographic data. To gain a better understanding of marine microbes that support the nutrient cycle and form the foundation of the food web, NTU scientists have embarked on a pilot project to crowd-source the collection of oceanographic data globally.

Initial research focused on optimization of the PMEMD classical molecular dynamics code, part of the widely used AMBER Molecular Dynamics software, on multi-core Intel Xeon processors and “manycore” Intel Xeon Phi processors.

SDSC Joins Intel Parallel Computing Centers Program with Focus on Molecular Dynamics, Neuroscience and Life Sciences

September 12, 2014 2:44 pm | by San Diego Supercomputer Center | News | Comments

The San Diego Supercomputer Center (SDSC) at the University of California, San Diego, is working with semiconductor chipmaker Intel to further optimize research software to improve the parallelism, efficiency, and scalability of widely used molecular and neurological simulation technologies.

Parents and physicians and scientists from the Neuroblastoma and Medulloblastoma Translational Research Consortium and TGen have teamed to launch a groundbreaking personalized medicine clinical trial investigation for pediatric cancer.

Providing Critical Child-cancer Research Tools to Speed Development of Personalized Treatments

September 11, 2014 3:25 pm | by TGen | News | Comments

Dell, Terascala and the Translational Genomics Research Institute are installing state-of-the-art computing and programing specialized for human genome investigations at the National Cancer Institute. The mission of the Oncogenomics Section at the NCI is to harness the power of high throughput genomic and proteomic methods to improve the outcome of children with high-risk metastatic, refractory and recurrent cancers.

Ralph Lauren Corp. is unveiling the high-performance, fashion-forward Polo Tech shirt on opening day of the US Open. The Polo Tech shirt is an innovative new product from a fashion brand that merges biometrics into active lifestyle apparel, marking a revo

Ralph Lauren Introduces the Next Evolution of Wearable Technology

September 3, 2014 3:33 pm | by Ralph Lauren Corporation | News | Comments

Ralph Lauren Corp. is unveiling the high-performance, fashion-forward Polo Tech shirt on opening day of the US Open. The Polo Tech shirt is an innovative new product from a fashion brand that merges biometrics into active lifestyle apparel, marking a revolution in advanced technology designed to improve general wellness and increase personal fitness.

The industry's preeminent event on Molecular Medicine, focusing on Drug Discovery, Genomics, Diagnostics and Information Technology.

22nd International Molecular Medicine Tri-Conference

August 28, 2014 3:17 pm | Events

The 22nd International Molecular Medicine Tri-Conference is the industry's Preeminent Event on Molecular Medicine, focusing on Drug Discovery, Genomics, Diagnostics and Information Technology. Spanning six days this year, the Tri-Conference includes an expanded program that includes 6 symposia, over 20 short courses, and 17 conference programs.

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The Expo provides the perfect venue to share information and discuss enabling technologies that are driving biomedical research and the drug development process

2015 Bio-IT World Conference & Expo

August 28, 2014 3:06 pm | Events

The 2015 Bio-IT World Conference & Expo plans to unite 3,000+ life sciences, pharmaceutical, clinical, healthcare, and IT professionals from 32+ countries. The Expo provides the perfect venue to share information and discuss enabling technologies that are driving biomedical research and the drug development process.

Pathogenic bacteria (red) live side-by-side with benign species (green) in a healthy mouth. Scientists are beginning to understand what causes bacterial communities to shift from health to diseases like periodontitis, diabetes, and Crohn's disease. Courte

Mouth Bacteria Can Change its Diet, Supercomputers Reveal

August 22, 2014 12:28 pm | by Jorge Salazar, TACC | News | Comments

Bacteria inside your mouth drastically change how they act when you're diseased. Scientists say these surprising findings might lead to better ways to prevent or even reverse the gum disease periodontitis, diabetes and Crohn's disease. UT Austin researchers used shotgun metagenomic sequencing, a non-targeted way to study the all the genetic material of the bacterial communities. They analyzed the RNA collected with  Lonestar and Stampede.

The Ebola virus viewed through an electron microscope. As of mid-2014, Ebola has caused two dozen outbreaks in Africa since the virus first emerged in 1976. (AP Photo/Antwerp Institute of Tropical Medicine)

Another Ebola Problem: Finding its Natural Source

August 18, 2014 12:25 pm | by Mike Stobbe and Marilynn Marchione, AP Medical Writers | News | Comments

A scary problem lurks beyond the frenzied efforts to keep people from spreading Ebola: No one knows exactly where the virus comes from or how to stop it from seeding new outbreaks. Ebola has caused two dozen outbreaks in Africa since it first emerged in 1976. It is coming from somewhere — probably bats — but experts agree they need to pinpoint its origins in nature.

Bain de Japonais Spring, an intertidal hydrothermal vent on Prony Bay. Courtesy of Roy Price, NASA

Our Ancestor’s Leaky Membrane answers Big Biology Questions

August 13, 2014 2:34 pm | by University College London | News | Comments

All life on Earth came from one common ancestor — a single-celled organism — but what it looked like, how it lived, and how it evolved into today’s modern cells is a four-billion-year-old mystery being solved by researchers using mathematical modeling. Findings suggest for the first time that life’s Last Universal Common Ancestor (LUCA) had a ‘leaky’ membrane, which helps scientists answer two of biology’s biggest questions...

An April memo from the EPA's chief of staff said that "unsolicited contacts" need to be "appropriately managed" and that committee members should refrain from directly responding to requests about committees' efforts to advise the agency.

Groups to EPA: Stop Muzzling Science Advisers

August 13, 2014 12:39 pm | by Dina Cappiello, Associated Press | News | Comments

Journalist and scientific organizations accused the EPA of attempting to muzzle its independent scientific advisers by directing them to funnel all outside requests for information through agency officials. In a letter on August 12, 2014, groups representing journalists and scientists urged the EPA to allow advisory board members to talk directly to news reporters, Congress and other outside groups without first asking for permission.

Seamlessly marrying electronics and brain signaling could transform how we treat some of the most puzzling and devastating diseases. Courtesy of Janulla

On the Frontiers of Cyborg Science: Seamless Marriage between Electronics and Brain Signaling

August 11, 2014 12:22 pm | by ACS | News | Comments

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits. Taking this human-machine concept to an unprecedented level, pioneering scientists are working on the seamless marriage between electronics and brain signaling, with the potential to transform our understanding of how to treat the brain's most devastating diseases.

A close-up of tiny bioink droplets used to print organs shows live cells inside. Courtesy of the American Chemical Society

Exploring 3-D Printing to Make Organs for Transplants

July 30, 2014 9:44 am | by American Chemical Society | News | Comments

Printing whole new organs for transplants sounds like something out of a sci-fi movie, but the real-life budding technology could one day make actual kidneys, livers, hearts and other organs for patients who desperately need them. In the ACS journal Langmuir, scientists are reporting new understanding about the dynamics of 3-D bioprinting that takes them a step closer to realizing their goal of making working tissues and organs on-demand.

ArxLab Notebook Web-based Electronic Notebook

ArxLab Notebook Web-based Electronic Notebook

July 29, 2014 3:15 pm | by Arxspan | Product Releases | Comments

ArxLab Notebook is a Web-based electronic notebook application. Its SaaS platform is intended for use in experimental sciences; it is preconfigured for chemistry and biology workflows while supporting free-form research notes and data. The software provides full audit trails, electronic signatures, witnessing workflows and built-in sharing functionality.

Computer Models Reveal Quantum Effects in Biological Oxygen Transport

July 18, 2014 3:41 pm | by Trinity College | News | Comments

Physicists have created a unique combination of computer models, based on the theory of quantum mechanics, and applied them to a previously well-characterized protein found in muscle to develop a new picture of how biomolecules transport and store oxygen (O2). In doing so, the team has shown how the process of respiration, which is fundamental in humans and other vertebrates, exploits quantum mechanical effects working on tiny scales.

Vampire Bat Venom Could Hold Key to New Drugs for Stroke, High Blood Pressure

July 15, 2014 4:38 pm | by University of Queensland | News | Comments

An international team of scientists has discovered that vampire bat venom contains molecules capable of evading the victim’s immune system. The results point to entirely new forms of anticoagulants in the venom, as well as novel molecules that cause dilation of the small arteries near the skin.

Brain Cancer Stem Cells from Human Brain Cancer Tissue

July 11, 2014 12:23 pm | News | Comments

This 200x photo of brain cancer stem cells from human brain cancer tissue received an Image of Distinction designation in the 2013 Nikon Small World Photomicrophotography Competition, which recognizes excellence in photography with the optical microscope. It was taken using immunofluorescence.

SLAS2015

July 11, 2014 10:24 am | by SLAS | Events

SLAS is a global organization that provides forums for education and information exchange to encourage study and professional collaboration aimed at advancing laboratory science and technology for the drug discovery, biotechnology, chemical, data informatics, clinical diagnostic, consumer product, pharmaceutical, and other industries.

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