Review and Critique of the MRHA Data Integrity Guidance for Industry — Part 4: System Design, Definitions and Overall AssessmentMay 29, 2015 1:56 pm | by R.D. McDowall, Ph.D. | Articles | Comments
This is the final part of a series reviewing and critiquing recent MHRAguidance for industry on data integrity. The first part of the series provided a background to the guidance document and discussed the introduction. The second part reviewed the data governance system, and the third part discussed data criticality and lifecycle. This part reviews the system design, some of the definitions, and finishes with an overall assessment.
Review and Critique of the MRHA Data Integrity Guidance for Industry — Part 3: Data Criticality and Data Life CycleMay 29, 2015 12:21 pm | by R.D. McDowall, Ph.D. | Articles | Comments
This is the third of a four-part series reviewing and critiquing the recent Medicines and...
Review and Critique of the MRHA Data Integrity Guidance for Industry — Part 2: Data Governance SystemMay 29, 2015 11:27 am | by R.D. McDowall, Ph.D. | Articles | Comments
This is the second of a four-part series reviewing and critiquing the recent Medicines and...
This new series of four articles takes a look at the new UK’s Medicines and Heathcare products...
All the computing power in the world isn’t useful if the software designed to access it is poorly designed. And we’re all much more discerning about user interfaces and usability: we expect our laboratory software to behave as intuitively as our smartphones. After all, laboratory employees are unlikely to be preoccupied with lines of codes and processors — they’re focused more on how easy the software is to use.
Benchling is a cloud-based platform that provides a suite of tools for life science - centered around a digital laboratory notebook - that accelerates R&D by tracking experiment details, facilitating collaboration, and streamlining data analysis.
A consortium of European space scientists has succeeded in establishing a common data hub that allows the comparison of data from numerous space missions. A task that until now was hampered by different data processing protocols of individual space missions. Furthermore, observational data can now easily be compared with theoretical numerical models — regardless of the protocols used.
Sentient Knowledge Explorer 5.1 is semantic data integration and knowledge management software for healthcare and life sciences. Both KE PRO and KE Personal Edition versions are available. Key features include the ability to save data, layout only or both, and to save as type TTL, NT, N3 or RDF.
Study Combines Field Experiments, Predictive Modeling to Look at How Forests Worldwide Respond to Climate ChangeApril 7, 2015 5:09 pm | by Oak Ridge National Laboratory | News | Comments
Researchers from the Department of Energy’s Oak Ridge National Laboratory will play key roles in an expansive new project that aims to bring the future of tropical forests and the climate system into much clearer focus by coupling field research with the development of a new ecosystem model.
Efficient, Time Sensitive Execution of Next-gen Sequencing Pipelines Critical for Translational MedicineApril 6, 2015 3:26 pm | by Suzanne Tracy, Editor-in-Chief, Scientific Computing and HPC Source | Blogs | Comments
Demand for genomics processing is rapidly spreading from research labs to the clinical arena. Genomics is now a "must have" tool for researchers in areas of oncology and rare diseases. It is also becoming a requirement in the clinical space for precision medicine, translational medicine and similar "bench to bedside" initiatives.
IBM announced that it will invest $3 billion over the next four years to establish a new Internet of Things (IoT) unit, and that it is building a cloud-based open platform designed to help clients and ecosystem partners build IoT solutions.
The phenomenon called aurora borealis in the Northern Hemisphere, and aurora australis in the Southern Hemisphere, is a dance of particles and magnetism between the Sun and Earth. Scientists hope that, by amassing data from thousands of aurora-viewers, they'll learn more about the solar storms that can disrupt or destroy Earth's communications networks and affect the planet's navigation, pipeline, electrical and transportation systems.
A new app for the iPad could change the way wildlife is monitored. Wildsense, an initiative from a group of researchers at the University of Surrey, is designed to use citizen science, the concept of allowing people to get directly involved in science, to help in the conservation of rare and endangered species.
Debra 6.2 laboratory information management system (LIMS) is designed for radiolabelled metabolism studies. The system offers a protocol set-up for adsorption/desorption studies, together with flexible reporting for all study parameters. Other key features include soil dispensing options for aqueous sediment study types, the ability to convert aliquot volumes to weights by addition of a density value ...
SampleManager LIMS is a comprehensive laboratory information management system. The integrated informatics solution comprises method execution, data visualization and laboratory management, and integrates with all popular enterprise-level software packages. It encompasses laboratory information management (LIMS), scientific data management (SDMS) and lab execution (LES).
Seahorse Scientific Workbench is a vendor-neutral software suite for capturing, analyzing and sharing analytical data. It consolidates raw and result data from multiple experimental techniques in a single tool, based on the emerging ASTM AnIML Data Standard. Seahorse Mobile delivers scientific data to mobile devices and supports chromatography (HPLC, GC), mass spectrometry, NMR, optical spectroscopy, microplate reader, bioreactor and fermenter, medical imaging and process chromatography data types.
If you were trying to forecast tomorrow's weather, you would probably look up at the sky rather than down at the ground. But if you live in the U.S. Midwest or someplace with a similar climate, one key to a better weather forecast may lie beneath your feet. Better soil moisture observations lead to better land-atmosphere interaction in weather forecasting models and ultimately to a better prediction of temperature and precipitation.
ACD/Labs 2015 cheminformatics software builds upon the capabilities of the ACD/Spectrus and ACD/Percepta platforms. The ACD/Spectrus Platform is designed to make it easier for organizations to handle unified analytical data from multiple techniques and instruments. The ACD/Percepta Platform features improvements in the speed of calculation of physicochemical and ADME-Tox properties and expanded capabilities to leverage organizational knowledge.
Registration is now open for a workshop on “Improving Data Mobility and Management for International Cosmology” to be held February 10-11, 2015, at Lawrence Berkeley National Laboratory in California. The workshop, one in a series of Cross-Connects workshops, is sponsored the by the Deptartment of Energy’s ESnet and Internet2. Early registration is encouraged, as attendance is limited.
Electronics and computer science researchers have helped to develop a new app to share world-class research and to receive the latest research news through a phone or tablet. The Software Sustainability Institute, a collaboration between the Universities of Southampton, Oxford, Edinburgh and Manchester, aims to spread the word about its work in promoting greater use of software in research.
This year's theme will focus on how to manage the change process in R&D and QA/QC laboratories of scientific organizations in pharmaceutical, biotechnology, consumer goods and chemical industries. The interactive congress will give actionable insights on how to adopt a new mindset in our daily work.
Over 14.7 million images were extracted from over 600 million pages covering an enormous variety of topics and stretching back to the year 1500. Yet, perhaps what is most remarkable about this montage is that these images come not from some newly-unearthed archive being seen for the first time, but rather from the books we have been digitizing for the past decade that have been resting in our digital libraries.
Institute for Quantitative and Computational Biosciences will Integrate Big Data to Solve Biomedical ProblemsDecember 22, 2014 4:05 pm | by Eryn Brown, UCLA | News | Comments
UCLA has announced a new institute to help medical and biology researchers make sense of 'big data.' Analyzing big data might help scientists understand how genes interact with the environment to promote good health or cause disease, and provide a clearer understanding of which medical treatments work best for particular populations, or in particular circumstances.
Of course, I remember the Berlin Wall being pummeled to gravel 25 years ago. I always hated what it symbolized, and I was excited. I was in Fayetteville, AR, at the finest hotel in town (a multi-story Holiday Inn at the time) when I saw the Germans storming the wall and whack-a-mole-ing the wall with ballpeen hammers. How I came to be in Arkansas is a rather remarkable and foreboding story.
As companies move from traditional physical infrastructure operated in house to cloud computing, there are several important factors they must take into consideration. With this in mind, Scientific Computing has published a special series that examines the impact of good manufacturing practice regulations on cloud computing.
Déjà Vu All Over Again: Knowledge management is not an IT problem, but a challenge to the culture of an organizationNovember 7, 2014 8:48 am | by Michael H. Elliott | Articles | Comments
In the late 1990s and the early 2000s, “Knowledge Management” (KM) was all the rage. Companies invested millions on enterprise content management (ECM) systems and teams of KM practitioners. It was believed that the codification of all knowledge assets across the enterprise would lead to new insights and higher levels of innovation.
Sometimes, words just complicate things. What if our brains could communicate directly with each other, bypassing the need for language? Researchers have successfully replicated a direct brain-to-brain connection between pairs of people as part of a scientific study following the team’s initial demonstration a year ago.
Earth is on pace to tie or even break the mark for the hottest year on record, federal meteorologists say. That's because global heat records have kept falling in 2014, with September the latest example. The National Oceanic and Atmospheric Administration announced October 20, 2014, that last month the globe averaged 60.3 degrees Fahrenheit (15.72 degrees Celsius). That was the hottest September in 135 years of record keeping.
The Oil and Gas High Performance Computing (HPC) Workshop, hosted annually at Rice University, is the premier meeting place for discussion of challenges and opportunities around high performance computing, information technology, and computational science and engineering.
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