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Big Data Approach to Bioinformatics Profiling Identifies New Mammalian Clock Gene

April 22, 2014 6:37 pm | by Penn Medicine | News | Comments

Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans. Over 15 mammalian clock proteins have been identified, but researchers surmise there are more. A team from the Perelman School of Medicine at the University of Pennsylvania wondered if big-data approaches could find them.

Alzheimer's-Cancer Link found using Biomedical Data, Supercomputing

April 22, 2014 3:35 pm | by Jorge Salazar, TACC | News | Comments

A team led by Houston Methodist Research Institute (HMRI) scientists has found that Alzheimer's...

Four-Eyed Daddy Longlegs Fossil Shows Arachnid had Extra Set of Eyes

April 11, 2014 10:03 am | by American Museum of Natural History | News | Comments

Living harvestmen — a group of arachnids more commonly known as daddy longlegs — have a single...

Bigger than Big Data: The Key to Successful Translational Science

April 4, 2014 9:13 am | by Robin Munro, IDBS | Blogs | Comments

Is Big Data really the biggest challenge at the moment for translational science? Certainly...

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Luis Serrano, Director, Center for Genomic Regulation (CRG), Spain

Luis Serrano

April 15, 2014 6:57 pm | Biographies

In our group we are aiming at a quantitative understanding of biological systems to an extent that one is able to predict systemic features and with the hope to rational design and modify their behavior. This applies to any system comprising biological components that is more than the mere sum of its components, or, in other words, the addition of the individual components results in systemic properties that could not be predicted by considering the components individually.

Four-Eyed Daddy Longlegs Fossil Shows Arachnid had Extra Set of Eyes

April 11, 2014 10:03 am | by American Museum of Natural History | News | Comments

Living harvestmen — a group of arachnids more commonly known as daddy longlegs — have a single pair of eyes that help them navigate habitats in every continent except Antarctica. But a newly described 305-million-year-old fossil found in eastern France shows that wasn’t always the case.

Bigger than Big Data: The Key to Successful Translational Science

April 4, 2014 9:13 am | by Robin Munro, IDBS | Blogs | Comments

Is Big Data really the biggest challenge at the moment for translational science? Certainly there are issues with the complexity and size of omics data, which Big Data techniques can help address, but there are two more pressing challenges: enabling collaboration whilst facilitating information sharing, and the ability to better interpret multiple different omics data (multi-omics).

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NY Genome Center, IBM Watson to Apply Advanced Analytics to Genomic Cancer Treatment

March 24, 2014 4:56 pm | by The New York Genome Center | News | Comments

The New York Genome Center (NYGC) and IBM announced an initiative to accelerate a new era of genomic medicine with the use of IBM's Watson cognitive system. IBM and NYGC will test a unique Watson prototype designed specifically for genomic research as a tool to help oncologists deliver more personalized care to cancer patients.

Sharp-clawed 'Chicken from Hell' Dinosaur Unveiled

March 19, 2014 8:36 pm | by University of Utah | News | Comments

Scientists from Carnegie and Smithsonian museums and the University of Utah have unveiled the discovery, naming and description of a sharp-clawed, 500-pound, bird-like dinosaur that roamed the Dakotas with T. rex 66 million years ago and looked like an 11 ½-foot-long "chicken from hell."

Klaus Schulten Talks about the Evolution of Computational Biophysics

March 14, 2014 10:26 am | by ISC | Articles | Comments

At this year's International Supercomputing Conference, Professor Klaus Schulten will deliver the opening keynote address on computing in biomedicine and bioengineering. Schulten, a physicist by training, now devotes his time to computation biophysics. He has contributed to several key discoveries in this area, has garnered numerous awards and honors for his work, and is considered one of preeminent leaders in field.

30,000-year-old Giant Virus found in Siberia

March 4, 2014 12:32 pm | News | Comments

A new type of giant virus called "Pithovirus" has been discovered in the frozen ground of extreme north-eastern Siberia. Buried underground, this giant virus, which is harmless to humans and animals, has survived being frozen for more than 30,000 years. It is the largest virus ever discovered.

NERSC Announces Second Annual HPC Achievement Awards

February 28, 2014 4:04 pm | by NERSC | News | Comments

The Department of Energy’s National Energy Research Scientific Computing Center (NERSC) announced the winners of its second annual High Performance Computing (HPC) Achievement Awards on February 4, 2014, during the annual NERSC User Group meeting at Lawrence Berkeley National Laboratory (Berkeley Lab).

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What’s the Hold-up? Stuck in Slime for a Billion Years

February 24, 2014 4:10 pm | by University of Tasmania | News | Comments

Researchers have revealed ancient conditions that almost ended life on Earth, using a new technique they developed to hunt for mineral deposits. The first life developed in the ancient oceans around 3.6 billion years ago, but then life remained as little more than a layer of slime for a billion years. Suddenly, 550 million years ago, evolution burst back into action. So, what was the hold-up during those ‘boring billion’ years?

Revolutionary Genome-based Naming System Proposed for All Life on Earth

February 21, 2014 5:48 pm | by Virginia Tech | News | Comments

A Virginia Tech researcher has developed a new way to classify and name organisms based on their genome sequence and in doing so created a universal language that scientists can use to communicate with unprecedented specificity about all life on Earth.

Whole Genome Analysis: When Each Patient is a Big Data Problem

February 20, 2014 11:28 am | by University of Chicago Medical Center | News | Comments

Although the time and cost of sequencing an entire human genome has plummeted, analyzing the resulting three billion base pairs of genetic information from a single genome can take many months. However, a team working with Beagle, one of the world's fastest supercomputers devoted to life sciences, reports that genome analysis can be radically accelerated. This computer is able to analyze 240 full genomes in about two days.

Ancient Baby DNA Suggests Tie to Native Americans

February 13, 2014 10:03 am | by Malcolm Ritter, AP Science Writer | News | Comments

The DNA of a baby boy who was buried in Montana 12,600 years ago has been recovered, and it provides new indications of the ancient roots of today's American Indians and other native peoples of the Americas. It's the oldest genome ever recovered from the New World. Artifacts found with the body show the boy was part of the Clovis culture, which existed in North America from about 13,000 years ago to about 12,600 years ago

Sequencing King Richard III’s Genetic Code

February 11, 2014 2:06 pm | by AP | News | Comments

Richard III has already been immortalized as Shakespeare's hunchbacked antihero. Now scientists hope to immortalize his genetic code by sequencing his DNA. Scientists believe the information will reveal the dead monarch's hair and eye color, provide insights into his ancestry, and even give some hints as to what ailed the infamous monarch, whose skeleton was unearthed beneath a parking lot in the English city of Leicester in 2012.

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800,000-year-old Footprints Discovered in England

February 10, 2014 4:33 pm | by Jill Lawless, Associated Press | News | Comments

They were a British family on a day out — almost a million years ago. Archaeologists announced February 7, 2014, that they have discovered human footprints in England that are between 800,000 and 1 million years old — the most ancient found outside Africa, and the earliest evidence of human life in northern Europe.

NERSC Flips Switch on New Flagship Supercomputer, Edison

January 31, 2014 2:21 pm | by Margie Wylie, Berkeley Lab | News | Comments

The National Energy Research Scientific Computing (NERSC) Center recently accepted “Edison,” a new flagship supercomputer designed for scientific productivity. Named in honor of American inventor Thomas Alva Edison, the Cray XC30 will be dedicated in a ceremony held at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) on February 5, 2014, and scientists are already reporting results.

Fossils Reveal Neanderthal DNA in Human Genome

January 30, 2014 2:58 pm | by Seth Borenstein, AP Science Writer | News | Comments

Next time you call someone a Neanderthal, better look in a mirror. Many of the genes that help determine most people's skin and hair are more Neanderthal than not, according to two new studies that look at the DNA fossils hidden in the modern human genome.

Accelerated Bioinformatics: CeBiTec FPGA Platform Runs Tera-BLAST Hundreds of Times Faster

January 28, 2014 12:29 pm | by TimeLogic | News | Comments

The Center for Biotechnology (CeBiTec) at Bielefeld University has added TimeLogic’s latest J-series Field Programmable Gate Array (FPGA) hardware to their computational tools platform. TimeLogic’s DeCypher systems are designed to greatly increase the speed of sequence comparison by combining custom FPGA circuitry with optimized implementations of BLAST, Smith-Waterman, Hidden Markov Model and gene modeling algorithms.

Crowdsourced RNA Designs Outperform Computer Algorithms, Carnegie Mellon, Stanford Researchers Say

January 27, 2014 9:19 pm | by Carnegie Mellon University | News | Comments

An enthusiastic group of non-experts, working through an online interface and receiving feedback from lab experiments, has produced designs for RNA molecules that are consistently more successful than those generated by the best computerized design algorithms, researchers at Carnegie Mellon University and Stanford University report.

Scientists Reveal Cause of One of the Most Devastating Pandemics in Human History

January 27, 2014 9:19 pm | by McMaster University | News | Comments

An international team of scientists has discovered that two of the world's most devastating plagues – the plague of Justinian and the Black Death, each responsible for killing as many as half the people in Europe—were caused by distinct strains of the same pathogen, one that faded out on its own, the other leading to worldwide spread and re-emergence in the late 1800s. These findings suggest a...

A Conversation with J. Craig Venter, Ph.D.: Goals for Digitizing Life

January 24, 2014 10:10 am | by Mary Ann Liebert, Publishers | News | Comments

"Life is a DNA software system" says J. Craig Venter, PhD, and biology can be digitized, the information sent via the Internet, and viruses and other life forms recreated using the emerging tools of synthetic biology. Dr. Venter describes his vision for applying biological teleportation to send digitized biological information around the world and from Mars to Earth in an interview in Industrial...

analytica 2014

January 23, 2014 9:41 am | by analytica | Events

From April 1 – 4, the International Trade Fair for Laboratory Technology, Analysis and Biotechnology will be a center for key players in science and industry. This year’s analytica will revolve around three main themes — i.e. food analysis, plastics analysis and genetic and bioanalysis—whether in the exhibition, the Live Labs and the program of related events.

Genedata Screener for Compound Combinations Platform

January 21, 2014 10:58 am | Genedata | Product Releases | Comments

The Genedata Screener for Compound Combinations platform provides for high-throughput combination screening capabilities within AstraZeneca's Oncology iMed unit. Automating and standardizing the data analysis of combination screening experiments, the platform accelerates discovery of new compound combination therapies by enabling high-throughput combination profiling.

Scientists Shed Light on Biological Dark Matter

January 19, 2014 11:00 pm | by UNIL/ Mediacom | News | Comments

Biologists have studied the functionality of a poorly understood category of genes, which produce long non-coding RNA molecules rather than proteins. Some of these genes have been conserved throughout evolution, and are present in 11 species ranging from man to frog. The research was lead at the University of Lausanne, in partnership with EPFL and the Swiss Institute of Bioinformatics. It has been published in Nature.

Amber Fossil Reveals Ancient Reproduction in Flowering Plants

January 3, 2014 10:36 am | by Oregon State University | News | Comments

A 100-million-year old piece of amber has been discovered which reveals the oldest evidence of sexual reproduction in a flowering plant – a cluster of 18 tiny flowers from the Cretaceous Period – with one of them in the process of making some new seeds for the next generation.

Observing the Sparks of Life: Researchers isolate photosynthetic complex in its complete functioning state

December 30, 2013 12:00 am | by U.S. Department Of Energy Office of Science | News | Comments

EFRC researchers isolate a photosynthetic complex — arguably the most important bit of organic chemistry on the planet — in its complete functioning state. When sunlight strikes a photosynthesizing organism, energy flashes between proteins just beneath its surface until it is trapped as separated electric charges. Improbable as it may seem, these tiny hits of energy eventually power the growth and movement of all plants and animals.

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