Enabling Innovation and Discovery through Data-Intensive High Performance Cloud and Big Data InfrastructureJuly 29, 2014 2:34 pm | by George Vacek, DataDirect Networks | Blogs | Comments
As the size and scale of life sciences datasets increases — think large-cohort longitudinal studies with multiple samples and multiple protocols — so does the challenge of storing, interpreting and analyzing this data. Researchers and data scientists are under increasing pressure to identify the most relevant and critical information within massive and messy data sets, so they can quickly make the next discovery.
Some 15 percent of adults suffer from fertility problems, many of these due to genetic factors....
SLAS is a global organization that provides forums for education and information exchange to...
Tandem protein mass spectrometry is one of the most widely used methods in proteomics, the large...
This 20x image of neuroprecursor stem cells undergoing neuronal differentiation received an Image of Distinction designation in the 2013 Nikon Small World Photomicrophotography Competition, which recognizes excellence in photography with the optical microscope. The confocal photo was taken by Regis Grailhe and Arnaud Ogier of Institut Pasteur Korea in Seongnam, Gyeonggi-do, South Korea.
Scientists discover and describe a new species of spider from Mexico. The new species belongs to the enigmatic family Paratropididae that is distinguished by representatives who possess unique camouflaging abilities.
Researchers have discovered seven new species of chirping giant pill-millipedes. The species discovered all belong to the genus Sphaeromimus, which is Latin for 'small ball animal.' However, the designation 'small' is not always true for members of the genus, as one of the newly discovered species surprises with a size larger than a ping-pong ball. Another special characteristic is the largest chirping organs of any millipede.
A dragon fish with intricate, maze-like markings on every scale, a frog with rough, chocolate-colored skin and a ginger plant are among more than two dozen flora and fauna species found in Myanmar since it emerged from a half-century of military rule and isolation.
A frontier lies deep within our cells. Our bodies are as vast as oceans and space, composed of a dizzying number of different types of cells. Exploration reaches far, yet the genes that make each cell and tissue unique have remained largely obscure. That’s changing with a search engine called EvoCor that identifies functionally linked genes.
A grandfather clock is, on its surface, a simple yet elegant machine. Tall and stately, its job is to steadily tick away the time. But a look inside reveals a much more intricate dance of parts, from precisely-fitted gears to cable-embraced pulleys and bobbing levers. Like exploring a clock's the inner workings, researchers are digging into the inner workings of the tiny cellular machines that help make all of the proteins our bodies need.
A species of snake that had been "lost" for almost 80 years has been re-discovered on a remote Mexican island. The Clarion nightsnake was found again on one of the Revillagigedo Islands, more than 400 miles (650 kilometers) off Mexico's Pacific coast, according to a study published in the PLOS ONE scientific journal.
Thousands of years ago, a teenage girl toppled into a deep hole in a Mexican cave and died. Now, her skeleton and her DNA are bolstering the long-held theory that humans arrived in the Americas by way of a land bridge from Asia. The girl's nearly complete skeleton was discovered by chance by expert divers who were mapping water-filled caves.
Preserved giant sperm from tiny shrimps that lived at least 17 million years ago have been discovered at the Riversleigh World Heritage Fossil Site in north Queensland, Australia, by a team including University of New South Wales (UNSW) Australia researchers.
Scientists showed that people who have a variant of a longevity gene, called KLOTHO, have improved brain skills such as thinking, learning and memory regardless of their age, sex, or whether they have a genetic risk factor for Alzheimer’s disease. Increasing KLOTHO gene levels in mice made them smarter, possibly by increasing the strength of connections between nerve cells in the brain.
Scientists have discovered 14 new species of so-called dancing frogs in the jungle mountains of southern India — just in time, they fear, to watch them fade away. Indian biologists say they found the tiny acrobatic amphibians, which earned their name with the unusual kicks they use to attract mates, declining dramatically in number during the 12 years in which they chronicled the species.
For the first time ever, a group of researchers has sequenced the genome of the spider. This knowledge provides a much more qualified basis for studying its features. It also shows that humans share certain genomic similarities with spiders. The fact that the eight-legged creepy spider in some ways resembles humans is one of the surprising conclusions ...
GeneMarker software includes an integrated replicate comparison tool for use in ecology, agricultural and clinical research. The tool automatically groups replicate samples within a project and provides immediate flagging to notify researchers of any discordant allele calls.
It is well established that modern humans originated in Africa, before moving out to inhabit rest of the planet. They first spread into Asia and Europe via the Arabian Peninsula, and those in the Far East eventually reached America and the Pacific islands. However, this simple picture does not explain several groups found across Asia and Oceania. Now, by looking at genetic and archaeological data, researchers might have found the answer
JMP Genomics 7.0 offers enhanced capabilities for analyzing data related to agriculture, pharmacogenomics, biotechnology and other areas for genomics research. It integrates sophisticated SAS statistical algorithms with interactive JMP data visualization to make discovery from life sciences data faster and easier.
Researcher Leonid Moroz emerges from a dive off the Florida Keys and gleefully displays a plastic bag holding a creature that shimmers like an opal in the seawater. This translucent animal and its similarly strange cousins are food for science. They regrow with amazing speed if they get chopped up. Some even regenerate a rudimentary brain. "Meet the aliens of the sea," the neurobiologist at the University of Florida says with a huge grin.
An international research team, including a George Washington University (GW) professor, has discovered and named the earliest and most primitive pterodactyloid — a group of flying reptiles that would go on to become the largest known flying creatures to have ever existed — and established they flew above the earth some 163 million years ago, longer than previously known.
Jeff Broughton is the NERSC Deputy for Operations and Systems Department Head, and has responsibility for acquiring, installing and operating all computational, networking and storage equipment for NERSC and the Joint Genome Institute. Current projects include NERSC-7 (Edison), the Computational Research and Theory Facility (CRT) which will be NERSC's new home, and DesignForward.
Dr. Collins is the director of the Advanced Biomedical Computing Center at the Frederick National Laboratory for Cancer Research. Dr. Collins’ research focuses on biomedical computing applications pertaining to cancer. His research group develops and applies high-performance algorithms to solve data-intensive computational biology problems in the areas of genomic analysis, pattern recognition in proteomics and imaging, molecular modeling, and systems biology.
Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans. Over 15 mammalian clock proteins have been identified, but researchers surmise there are more. A team from the Perelman School of Medicine at the University of Pennsylvania wondered if big-data approaches could find them.
A team led by Houston Methodist Research Institute (HMRI) scientists has found that Alzheimer's disease and cancer share a pathway in gene transcription, a process essential for cell reproduction and growth. They published their findings in December 2013 in the open access journal Scientific Reports by the Nature Publishing Group.
In our group we are aiming at a quantitative understanding of biological systems to an extent that one is able to predict systemic features and with the hope to rational design and modify their behavior. This applies to any system comprising biological components that is more than the mere sum of its components, or, in other words, the addition of the individual components results in systemic properties that could not be predicted by considering the components individually.
Living harvestmen — a group of arachnids more commonly known as daddy longlegs — have a single pair of eyes that help them navigate habitats in every continent except Antarctica. But a newly described 305-million-year-old fossil found in eastern France shows that wasn’t always the case.
Is Big Data really the biggest challenge at the moment for translational science? Certainly there are issues with the complexity and size of omics data, which Big Data techniques can help address, but there are two more pressing challenges: enabling collaboration whilst facilitating information sharing, and the ability to better interpret multiple different omics data (multi-omics).
The New York Genome Center (NYGC) and IBM announced an initiative to accelerate a new era of genomic medicine with the use of IBM's Watson cognitive system. IBM and NYGC will test a unique Watson prototype designed specifically for genomic research as a tool to help oncologists deliver more personalized care to cancer patients.
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