Big data: It’s a term we read and hear about often, but is hard to grasp. Computer scientists tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases. Through a novel method of analyzing these big data, they discovered a region encompassing the gephyrin gene on chromosome 14 that underwent rapid evolution after splitting in two...
The World Health Organization reports that cardiovascular diseases are the number one cause of...
SLIM (Stability Lab Information Manager) is a fully validated LIMS designed for complete...
The intraterrestrials, they might be called. Strange creatures live in the deep sea, but few are odder than the viruses that inhabit deep ocean methane seeps and prey on single-celled microorganisms called archaea. The least understood of life's three primary domains, archaea thrive in the most extreme environments: near hot ocean rift vents, in acid mine drainage, in the saltiest of evaporation ponds and in petroleum deposits.
A newly discovered crocodilian ancestor may have filled one of North America's top predator roles before dinosaurs arrived on the continent. The "Carolina Butcher" was a nine-foot-long, land-dwelling crocodylomorph that walked on its hind legs and likely preyed upon smaller inhabitants of North Carolina ecosystems, such as armored reptiles and early mammal relatives.
In 1996, a trio of scientists won the Nobel Prize for Chemistry for their discovery of Buckminsterfullerene — soccer-ball-shaped spheres of 60 joined carbon atoms that exhibit special physical properties. Now, 20 years later, scientists have figured out how to turn them into Buckybombs. These nanoscale explosives show potential for use in fighting cancer, with the hope that they could target and eliminate cancer at the cellular level.
Breaking new grounds in the future of remote-controlled drone technology, researchers have developed a living machine whose flight can be wirelessly controlled with minimal human intervention. Mounted on top of a giant flower beetle, a tiny, electronic backpack with a built-in wireless receiver and transmitter converts radio signals received remotely into a variety of actions in the beetle.
Breakthrough science requires pioneers. People who combine brilliance with courage, even in the face of daunting opposition. The women who paved the way for modern scientific exploration exemplify this spirit; grappling not only with fundamental questions of the universe, but with discrimination and societal constraints that often stripped them of scientific credit.
A new app for the iPad could change the way wildlife is monitored. Wildsense, an initiative from a group of researchers at the University of Surrey, is designed to use citizen science, the concept of allowing people to get directly involved in science, to help in the conservation of rare and endangered species.
TITAN is a Web-based enterprise resource planning (ERP)/laboratory information management system (LIMS) with integrated Report Designer, Workflow and Artifact Designer tools. It features three layers: a Laboratory Layer for management of laboratory functions from sample tracking to final disposition, facilitation of ISO 17025 compliance, e-sigs for custom workflows ...
Solving Puzzle-Like Bond for Biofuels: First Look at One of Nature's Strongest Biomolecular InteractionsMarch 17, 2015 3:02 pm | by Texas Advanced Computing Center | News | Comments
One of life's strongest bonds has been discovered by a science team researching biofuels with the help of supercomputers. Their find could boost efforts to develop catalysts for biofuel production from non-food waste plants. Renowned computational biologist Klaus Schulten of the University of Illinois at Urbana-Champaign led the analysis and modeling of the bond, which behaves like a Chinese Finger Trap puzzle.
A means of reprogramming a flawed immune response into an efficient anti-tumoral one was brought to light by the results of a translational trial relating to breast cancer. Thanks to the innovative combination of mathematical modeling and experimentation, only 20 tests were necessary, whereas traditional experimentation would have required 596 tests to obtain the same results.
University of Pittsburgh, Carnegie Mellon University, UPMC Form Alliance to Transform Healthcare through Big DataMarch 17, 2015 2:19 pm | by UPMC | News | Comments
Today’s health care system generates massive amounts of data — electronic health records, diagnostic imaging, prescriptions, genomic profiles, insurance records, even data from wearable devices. Information has always been essential for guiding care, but computer tools now make it possible to use that data to provide deeper insights. Leveraging big data to revolutionize healthcare is the focus of the Pittsburgh Health Data Alliance.
Researchers have achieved the first “image fusion” of mass spectrometry and microscopy — a technical tour de force that could, among other things, dramatically improve the diagnosis and treatment of cancer. Using a mathematical approach called regression analysis, they mapped each pixel of mass spectrometry data onto the corresponding spot on the microscopy image to produce a new, “predicted” image.
Debra 6.2 laboratory information management system (LIMS) is designed for radiolabelled metabolism studies. The system offers a protocol set-up for adsorption/desorption studies, together with flexible reporting for all study parameters. Other key features include soil dispensing options for aqueous sediment study types, the ability to convert aliquot volumes to weights by addition of a density value ...
Studying the intricate fractal patterns on the surface of cells could give researchers a new insight into the physical nature of cancer, and provide new ways of preventing the disease from developing. This is according to scientists who have, for the first time, shown how physical fractal patterns emerge on the surface of human cancer cells at a specific point of progression towards cancer.
The international robotics community has turned out in force for the DARPA Robotics Challenge Finals, a competition of robots and their human supervisors to be held June 5 to 6 outside of Los Angeles. In the competition, human-robot teams will be tested on capabilities that could enable them to provide assistance in future natural and man-made disasters.
A high-speed camera for monitoring vegetation from space and combating famine in Africa is being adapted to spot changes in human skin cells, invisible to the naked eye, to help diagnose skin diseases like cancer. In fact, the extraordinary digital infrared sensor from ESA’s Proba-V vegetation-scanning satellite is being adapted for several non-space applications.
SampleManager LIMS is a comprehensive laboratory information management system. The integrated informatics solution comprises method execution, data visualization and laboratory management, and integrates with all popular enterprise-level software packages. It encompasses laboratory information management (LIMS), scientific data management (SDMS) and lab execution (LES).
Seahorse Scientific Workbench is a vendor-neutral software suite for capturing, analyzing and sharing analytical data. It consolidates raw and result data from multiple experimental techniques in a single tool, based on the emerging ASTM AnIML Data Standard. Seahorse Mobile delivers scientific data to mobile devices and supports chromatography (HPLC, GC), mass spectrometry, NMR, optical spectroscopy, microplate reader, bioreactor and fermenter, medical imaging and process chromatography data types.
The ACD/Spectrus Portal is a Web-based interface that provides vendor neutral, multi-technique results from analytical chemistry experiments to laboratory chemists. The portal extends the ACD/Spectrus analytical and chemical laboratory intelligence platform through a series of domain-specific market applications.
Pharmaceutical companies are under intense pressure. With patents expiring and cost pressures growing, the speed and productivity of drug discovery and manufacturing are under the microscope. It is timely, then, that researchers recently shared promising findings on Eve — an artificially-intelligent robot scientist. Eve discovered a compound with anti-cancer properties. Is this a glimpse of what the lab of the future might look like?
The LabWare 7 enterprise laboratory platform brings together the capabilities of laboratory information management systems (LIMS) and electronic laboratory notebooks (ELN) in a single comprehensive solution. It is an adaptable and functionally complete LIMS system scalable to suit every size organization, from single-site, single-user to global organizations with 1000s of users.
Scientists have long known that our ability to think quickly and recall information, also known as fluid intelligence, peaks around age 20 and then begins a slow decline. However, more recent findings, including a new study from neuroscientists at MIT and Massachusetts General Hospital (MGH), suggest that the real picture is much more complex.
A National Institutes of Health-led public-private partnership to transform and accelerate drug development achieved a significant milestone recently with the launch of a new Alzheimer’s Big Data portal — including delivery of the first wave of data — for use by the research community.
For the first time, researchers have produced a 3-D image revealing part of the inner structure of an intact, infectious virus, using a unique X-ray laser. The virus, called Mimivirus, is in a curious class of “giant viruses” discovered just over a decade ago. The experiment establishes a new technique for reconstructing the 3-D structure of many types of biological samples from a series of X-ray laser snapshots.
Researchers focusing on a fictional zombie outbreak as an approach to disease modeling suggest heading for the hills, in the Rockies, to save your brains from the undead. Reading World War Z: An Oral History of the First Zombie War, and taking a graduate statistical mechanics class inspired a group of Cornell University researchers to explore how an "actual" zombie outbreak might play out in the U.S.
Liquid water is a requirement for life on Earth. But in other, much colder worlds, life might exist beyond the bounds of water-based chemistry. Taking a simultaneously imaginative and rigidly scientific view, chemical engineers and astronomers offer a template for life that could thrive in a harsh, cold world — specifically Titan, the giant moon of Saturn.
- Page 1