Tandem protein mass spectrometry is one of the most widely used methods in proteomics, the large-scale study of proteins, particularly their structures and functions. Researchers in the Marcotte group at the University of Texas at Austin are using the Stampede supercomputer to develop and test computer algorithms that let them more accurately and efficiently interpret proteomics mass spectrometry data.
The Program Committee has announced a call for papers for the Pittcon 2015 Technical Program....
This colorful cosmic rainbow portrays a section of Saturn’s beautiful rings, four centuries...
The Clarity MS Extension control driver for Advion’s expression compact mass spectrometers (CMS) includes both digital control of the detector and digital data acquisition of the detector signal. It also allows performance of all service operations necessary for the detector from the Device Monitor software window.
Scientists are using powerful analytical and imaging tools to study artworks from all ages, delving deep below the surface to reveal the process and materials used by some of the world’s greatest artists. Chemist Richard Van Duyne, in collaboration with conservation scientists at the Art Institute of Chicago, has been using a scientific method to investigate masterpieces by Pierre-Auguste Renoir, Winslow Homer and Mary Cassatt.
Tens of thousands of pot smokers wheezed a sigh of relief when recreational marijuana use was made legal January 1, 2014. Gone is the cottage industry of gray-area physicians rubber-stamping medical prescriptions for a well-informed gaggle of would-be stoners who memorized popular conditions sure to garner approval.
When life on Earth was first getting started, simple molecules bonded together into the precursors of modern genetic material. A catalyst would have been needed, but enzymes had not yet evolved. One theory is that the catalytic minerals on a meteorite’s surface could have jump-started life’s first chemical reactions. But scientists need a way to directly analyze these rough, irregularly shaped surfaces.
Creating surrogate human organs, coupled with insights from highly sensitive mass spectrometry technologies, a new project is on the brink of revolutionizing the way we screen new drugs and toxic agents.
For the first time, the ASACUSA experiment at CERN has succeeded in producing a beam of antihydrogen atoms. Primordial antimatter has so far never been observed in the Universe, and its absence remains a major scientific enigma. Nevertheless, it is possible to produce significant amounts of antihydrogen in experiments at CERN by mixing antielectrons (positrons) and low energy antiprotons produced by the Antiproton Decelerator.
The Pittcon Organizing Committee has announced that Innovative Publishing, producer of Food Labs Conference and publisher of Food Safety Tech eJournal, has signed an agreement for the second year for the co-location of Food Labs Conference to be held in conjunction with Pittcon 2014.
Ah, 30,000 feet and some old Dire Straits on the headphones, and waiting for my warm Heineken. Perfect. Though I enjoy lambasting companies that get it wrong, I’m also quick to stomp my feet and clap my hands when companies get it right. And I’ll do that, I promise, but allow me my fun first.
A new imaging method for analyzing biological samples based on their chemical makeup is set to transform the way medical scientists examine diseased tissue. Researchers at Imperial College London have outlined a recipe for processing mass spectrometry imaging data and building a database of tissue types.
Data Integrity in a Nutshell: Industry must take bold steps to assure the data used for drug quality decisions is trustworthyJanuary 7, 2014 12:31 pm | by Mark E. Newton | Articles | Comments
Regulatory inspectors have started digging much deeper into data, no longer accepting batch release data and supportive testing at face value. Even worse, this effort is justified: they have cited a number of firms for violations of data integrity, a most fundamental bond of trust between manufacturers and the regulators that inspect them. Industry must take bold steps to assure the data used for drug quality decisions is trustworthy...
Data integrity is a current hot topic with regulatory agencies, as seen with recent publications in this magazine, and audit trails are an important aspect of ensuring this in computerized systems. The purpose of this article is to compare and contrast the EU and FDA GMP regulatory requirements for computerized system audit trails.
One of the challenges in laboratory data management is the handling and exchange of experiment data. Many vendors provide excellent instruments, but most produce data in their own proprietary formats. This leads to major difficulties for data processing, collaboration, instrument integration and archiving. The ASTM AnIML standardization effort addresses these problems by providing a neutral XML-based format for exchanging scientific data.
The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy announced the 2014 Technical Program that includes over 2,000 presentations offered in symposia, oral sessions, workshops, awards and posters. This year’s program covers a wide range of applications such as biotechnology, biomedical, drug discovery, environmental, food science, fuels/energy, lab management, nanotechnology, polymers/plastics and regulations.
The Society for Laboratory Automation and Screening (SLAS) Young Scientist Awards Program will honor achievement by three students at SLAS2014, the Third Annual SLAS Conference and Exhibition, which will be held January 18 to 22, 2014, at the San Diego Convention Center in San Diego, CA.
The ever-increasing threat from "superbugs" -- strains of pathogenic bacteria that are impervious to the antibiotics that subdued their predecessor generations -- has forced the medical community to look for bactericidal weapons outside the realm of traditional drugs. One promising candidate is the antimicrobial peptide (AMP), one of Mother Nature's lesser-known defenses against infections, that...
Kepler-78b is a planet that shouldn't exist. This scorching lava world circles its star every eight and a half hours at a distance of less than one million miles - one of the tightest known orbits. According to current theories of planet formation, it couldn't have formed so close to its star, nor could it have moved there.
Dramatic advances in the field of quantum dot light emitting diodes (QD-LEDs) could come from recent work by the Nanotechnology and Advanced Spectroscopy team at Los Alamos National Laboratory. Quantum dots are nano-sized semiconductor particles whose emission color can be tuned by simply changing their dimensions.
The new HITS research group “Astroinformatics” will develop methods and software for astronomers and help facilitating the analysis and processing of the rapidly growing amount of data in astronomy. The junior group led by Kai Polsterer will work closely with other astronomical research groups in Heidelberg.
The Pittcon Organizing Committee has recently announced the topics for Conferee Networking during Pittcon 2014, which will be in Chicago, Illinois, McCormick Place, March 2 to 6, 2014. Conferee Networking sessions are free to all registered attendees and provide an informal venue for a small group of participants to openly discuss topics of mutual interest or solve problems specific to certain instrumentation or procedures.
Astrophysicists have found the first evidence of a water-rich rocky planetary body outside our solar system in its shattered remains orbiting a white dwarf. A new study by scientists at the Universities of Warwick and Cambridge published in the journalScience analyzed the dust and debris surrounding the white dwarf star GD61 170 light years away.
The Pittcon Organizing Committee has announces the course listing for the 2014 Short Course program which runs March 1 through March 6, 2014. Short Courses are taught by industry experts; range from half-day up to two-day classes; and include beginner, intermediate, and advanced level curricula.
Reliable quantum computing would make it possible to solve certain types of extremely complex technological problems millions of times faster than today's most powerful supercomputers. Other types of problems that quantum computing could tackle would not even be feasible with today's fastest machines. The key word is "reliable." If the enormous potential of quantum computing is to be fully...
A further look at this current emphasis and a few problems inspectors have identified. The integrity of data generated by a regulated laboratory can make or break a regulatory inspection or audit. If you think that the warning letter citations quoted in part 1 of this article were bad, give a thought for another company...
The integrity of data generated by a regulated laboratory can make or break a regulatory inspection or audit. This paper looks at what is required for data integrity from the basis of the GMP regulations. It presents examples of non-compliances found in warning letters and a regulatory action from the U.S. Food and Drug Administraqtion (FDA).
KnowItAll Informatics System 2013 spectroscopy software is designed to offer comprehensive solutions for spectral analysis, identification, search, data management and reporting. It supports multiple instrument vendor file formats and techniques
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