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The Lead

Robotic Arm Probes Chemistry of 3-D Objects

April 11, 2014 9:53 am | by Brett Israel, Georgia Tech | News | Comments

When life on Earth was first getting started, simple molecules bonded together into the precursors of modern genetic material. A catalyst would have been needed, but enzymes had not yet evolved. One theory is that the catalytic minerals on a meteorite’s surface could have jump-started life’s first chemical reactions. But scientists need a way to directly analyze these rough, irregularly shaped surfaces.

Desktop Human Could Reduce Animal Drug Tests

March 26, 2014 7:08 pm | by Los Alamos National Laboratory | News | Comments

Creating surrogate human organs, coupled with insights from highly sensitive mass spectrometry...

CERN Experiment Produces First Beam of Antihydrogen Atoms for Hyperfine Study

January 23, 2014 10:30 am | by CERN | News | Comments

For the first time, the ASACUSA experiment at CERN has succeeded in producing a beam of...

Pittcon, Food Labs Conference Announce Co-location

January 20, 2014 2:45 pm | by Pittcon | News | Comments

The Pittcon Organizing Committee has announced that Innovative Publishing, producer of Food Labs...

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Kiss my Turbine: What Electronics Firms Can Learn from the Doomed Airline Industry

January 13, 2014 4:39 pm | by Randy C. Hice | Blogs | Comments

Ah, 30,000 feet and some old Dire Straits on the headphones, and waiting for my warm Heineken. Perfect. Though I enjoy lambasting companies that get it wrong, I’m also quick to stomp my feet and clap my hands when companies get it right. And I’ll do that, I promise, but allow me my fun first.

Chemical Imaging brings Cancer Tissue Analysis into Digital Age

January 8, 2014 7:13 am | by Imperial College London | News | Comments

A new imaging method for analyzing biological samples based on their chemical makeup is set to transform the way medical scientists examine diseased tissue. Researchers at Imperial College London have outlined a recipe for processing mass spectrometry imaging data and building a database of tissue types.

Data Integrity in a Nutshell: Industry must take bold steps to assure the data used for drug quality decisions is trustworthy

January 7, 2014 12:31 pm | by Mark E. Newton | Articles | Comments

Regulatory inspectors have started digging much deeper into data, no longer accepting batch release data and supportive testing at face value. Even worse, this effort is justified: they have cited a number of firms for violations of data integrity, a most fundamental bond of trust between manufacturers and the regulators that inspect them. Industry must take bold steps to assure the data used for drug quality decisions is trustworthy...

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Comparison of FDA and EU Regulations for Audit Trails

January 7, 2014 12:02 pm | by R.D. McDowall | Articles | Comments

Data integrity is a current hot topic with regulatory agencies, as seen with recent publications in this magazine, and audit trails are an important aspect of ensuring this in computerized systems. The purpose of this article is to compare and contrast the EU and FDA GMP regulatory requirements for computerized system audit trails.

A Fresh Look at the AnIML Data Standard

January 7, 2014 11:47 am | by Burkhard Schaefer | Articles | Comments

One of the challenges in laboratory data management is the handling and exchange of experiment data. Many vendors provide excellent instruments, but most produce data in their own proprietary formats. This leads to major difficulties for data processing, collaboration, instrument integration and archiving. The ASTM AnIML standardization effort addresses these problems by providing a neutral XML-based format for exchanging scientific data.

Pittcon Announces 2014 Technical Program

December 13, 2013 9:27 am | News | Comments

The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy announced the 2014 Technical Program  that includes over 2,000 presentations offered in symposia, oral sessions, workshops, awards and posters. This year’s program covers a wide range of applications such as biotechnology, biomedical, drug discovery, environmental, food science, fuels/energy, lab management, nanotechnology, polymers/plastics and regulations.

Young Scientist Awards Brings Global Participants to SLAS2014

December 3, 2013 3:27 pm | by SLAS | News | Comments

The Society for Laboratory Automation and Screening (SLAS) Young Scientist Awards Program will honor achievement by three students at SLAS2014, the Third Annual SLAS Conference and Exhibition, which will be held January 18 to 22, 2014, at the San Diego Convention Center in San Diego, CA.

A New Weapon in the Fight against Superbugs

November 1, 2013 9:14 am | by American Institute of Physics | News | Comments

The ever-increasing threat from "superbugs" -- strains of pathogenic bacteria that are impervious to the antibiotics that subdued their predecessor generations -- has forced the medical community to look for bactericidal weapons outside the realm of traditional drugs. One promising candidate is the antimicrobial peptide (AMP), one of Mother Nature's lesser-known defenses against infections, that...

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Mystery World Baffles Astronomers

October 30, 2013 6:37 pm | by Harvard-Smithsonian Center for Astrophysics | News | Comments

Kepler-78b is a planet that shouldn't exist. This scorching lava world circles its star every eight and a half hours at a distance of less than one million miles - one of the tightest known orbits. According to current theories of planet formation, it couldn't have formed so close to its star, nor could it have moved there.

Nanoscale Engineering: Making the Light at the End of the Tunnel More Efficient

October 30, 2013 2:38 pm | by Los Alamos National Laboratory | News | Comments

Dramatic advances in the field of quantum dot light emitting diodes (QD-LEDs) could come from recent work by the Nanotechnology and Advanced Spectroscopy team at Los Alamos National Laboratory. Quantum dots are nano-sized semiconductor particles whose emission color can be tuned by simply changing their dimensions.

Astroinformatics Helps Astronomers Explore the Sky

October 28, 2013 8:20 am | by Heidelberg Institute for Theoretical Studies | News | Comments

The new HITS research group “Astroinformatics” will develop methods and software for astronomers and help facilitating the analysis and processing of the rapidly growing amount of data in astronomy. The junior group led by Kai Polsterer will work closely with other astronomical research groups in Heidelberg.

Pittcon Announces Topics for Conferee Networking Sessions

October 16, 2013 12:12 pm | by The Pittsburgh Conference | News | Comments

The Pittcon Organizing Committee has recently announced the topics for Conferee Networking during Pittcon 2014, which will be in Chicago, Illinois, McCormick Place, March 2 to 6, 2014. Conferee Networking sessions are free to all registered attendees and provide an informal venue for a small group of participants to openly discuss topics of mutual interest or solve problems specific to certain instrumentation or procedures.

Water Discovered in Remnants of Extrasolar Rocky World

October 14, 2013 1:58 pm | by University of Warwick | News | Comments

Astrophysicists have found the first evidence of a water-rich rocky planetary body outside our solar system in its shattered remains orbiting a white dwarf. A new study by scientists at the Universities of Warwick and Cambridge published in the journalScience analyzed the dust and debris surrounding the white dwarf star GD61 170 light years away.

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Pittcon Announces 2014 Short Course Program

October 1, 2013 3:05 pm | by Pittcon | News | Comments

The Pittcon Organizing Committee has announces the course listing for the 2014 Short Course program which runs March 1 through March 6, 2014. Short Courses are taught by industry experts; range from half-day up to two-day classes; and include beginner, intermediate, and advanced level curricula.

On the Road to Fault-tolerant Quantum Computing

September 16, 2013 5:33 pm | by Lawrence Berkeley National Laboratory | News | Comments

Reliable quantum computing would make it possible to solve certain types of extremely complex technological problems millions of times faster than today's most powerful supercomputers. Other types of problems that quantum computing could tackle would not even be feasible with today's fastest machines. The key word is "reliable." If the enormous potential of quantum computing is to be fully...

FDA’s Focus on Laboratory Data Integrity – Part 2

September 15, 2013 3:31 pm | by R.D. McDowall | Articles | Comments

A further look at this current emphasis and a few problems inspectors have identified. The integrity of data generated by a regulated laboratory can make or break a regulatory inspection or audit. If you think that the warning letter citations quoted in part 1 of this article were bad, give a thought for another company...

FDA’s Focus on Laboratory Data Integrity – Part 1

September 10, 2013 3:04 pm | by R.D. McDowall | Articles | Comments

The integrity of data generated by a regulated laboratory can make or break a regulatory inspection or audit. This paper looks at what is required for data integrity from the basis of the GMP regulations. It presents examples of non-compliances found in warning letters and a regulatory action from the U.S. Food and Drug Administraqtion (FDA).

KnowItAll Informatics System 2013 Spectroscopy Software

September 3, 2013 12:23 pm | Bio-Rad Laboratories | Product Releases | Comments

KnowItAll Informatics System 2013 spectroscopy software is designed to offer comprehensive solutions for spectral analysis, identification, search, data management and reporting. It supports multiple instrument vendor file formats and techniques

Pittcon Calls for Topics for Conferee Networking Sessions

July 31, 2013 2:38 pm | by Pittcon | News | Comments

The Conferee Networking committee is pleased to announce its annual Call for Topics for Conferee Networking sessions, which will take place during Pittcon 2014 at McCormick Place, Chicago, IL, March 2 to 6, 2014. These two-hour sessions provide a unique networking opportunity for attendees with similar interests to meet and resolve problems, discuss new techniques, or brainstorm new ideas in an informal setting.

Seeing Photosynthesis from Space: NASA Uses Satellites to Measure Plant Health

July 24, 2013 5:41 pm | by NASA | News | Comments

NASA scientists have established a new way to use satellites to measure what's occurring inside plants at a cellular level. Plants grow and thrive through photosynthesis, a process that converts sunlight into energy. During photosynthesis, plants emit what is called fluorescence

Stargazer Takes Off with IRIS Solar Observatory

July 22, 2013 10:52 am | News | Comments

The Orbital Sciences L-1011 aircraft takes off from Vandenberg Air Force Base in California at 9:30 p.m. EDT on June 27, 2013, headed over the Pacific Ocean to release the Pegasus XL rocket carrying NASA's Interface Region Imaging Spectrograph, or IRIS, solar observatory.

New Nanoscale Imaging Method Finds Application in Plasmonics

July 16, 2013 4:14 pm | by National Institute of Standards and Technology (NIST) | News | Comments

Researchers from the National Institute of Standards and Technology (NIST) and the University of Maryland have shown how to make nanoscale measurements of critical properties of plasmonic nanomaterials—the specially engineered nanostructures that modify the interaction of light and matter for a variety of applications, including sensors, cloaking (invisibility), photovoltaics and therapeutics.

ORNL wins Six R&D 100s

July 9, 2013 3:40 pm | by ORNL | News | Comments

Researchers at the Department of Energy's Oak Ridge National Laboratory have received six R&D 100 awards, presented each year by R&D Magazine in recognition of the year's most significant technological innovations. The six awards bring ORNL's total of R&D 100 awards to 179 since their inception in 1963.

Tiny Nanocubes Know Left from Right

June 28, 2013 10:59 am | by Brookhaven National Laboratory | News | Comments

In chemical reactions, left and right can make a big difference. A "left-handed" molecule of a particular chemical composition could be an effective drug, while its mirror-image "right-handed" counterpart could be completely inactive. That's because, in biology, "left" and "right" molecular designs are crucial: Living organisms are made only from left-handed amino acids. So telling the...

IRIS Set for Launch

June 27, 2013 7:15 pm | by NASA | News | Comments

Technicians and engineers at Vandenberg Air Force Base in California mate the Pegasus XL rocket with the Interface Region Imaging Spectrograph, or IRIS, solar observatory to the Orbital Sciences L-1011 carrier aircraft. IRIS will open a new window of discovery by tracing the flow of energy and plasma through the chromospheres and transition region into the sun’s corona using spectrometry and imaging.

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