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The Alan Turing Institute will promote the development and use of advanced mathematics, computer science, algorithms and big data for human benefit.

Alan Turing Institute Positioned to Break New Big Data, Online Security Boundaries

January 30, 2015 11:41 am | by Engineering and Physical Sciences Research Council | News | Comments

The five universities have been selected to lead the new Alan Turing Institute. The Institute will build on the UK's existing academic strengths and help position the country as a world leader in the analysis and application of big data and algorithm research. Its headquarters will be based at the British Library at the center of London’s Knowledge Quarter.

Needle in a Haystack: Finding the Right Genes in Tens of Thousands

January 28, 2015 2:45 pm | by TACC | News | Comments

Scientists using supercomputers found genes sensitive to cold and drought in a plant help it...

We're Two Minutes Closer to Doomsday

January 23, 2015 2:49 pm | by Seth Borenstein, AP Science Writer | News | Comments

The Bulletin of the Atomic Scientists says Earth is now closer to human-caused doomsday than it...

Optimizing Optimization Algorithms: How to Get the Best Results

January 23, 2015 2:36 pm | by Larry Hardesty, MIT | News | Comments

Optimization algorithms, which try to find the minimum values of mathematical functions, are...

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Partek Flow 4.0 for NGS Analysis

Partek Flow 4.0 for NGS Analysis

January 22, 2015 1:51 pm | Partek Incorporated | Product Releases | Comments

Partek Flow 4.0 is designed specifically for the analysis needs of next-generation sequencing applications including RNA, small RNA and DNA sequencing. With the ability to either build custom analysis pipelines or download pre-built pipelines, users can perform alignment, quantification, quality control, statistics and visualization.

Mark Anawis is a Principal Scientist and ASQ Six Sigma Black Belt at Abbott.

The Power of Regular Expressions

January 22, 2015 10:49 am | by Mark A. Anawis | Blogs | Comments

A.J. Jacobs wrote: “I think there's something to the idea that the divine dwells more easily in text than in images.” Since there has been an explosion in the amount of text, sacred and secular, available to anyone with an Internet connection, the need for processing tools has grown. Regular expressions can be used to extract specific text from documents due to their ability to replace many lines of code with as little as one line.

John Wass is a statistician based in Chicago, IL.

Book Review: Applied Bayesian Modelling, 2nd Edition

January 13, 2015 8:59 am | by John A. Wass, Ph.D. | Articles | Comments

This is not a text for the novice. However, for those math/statistics aficionados, there is much to be had. The book’s great strength lies in two areas: the first is Peter Congdon’s generation of an excellent bibliography of the most modern techniques available, and the other is his (slightly) more straightforward explanations of the strengths and weaknesses of these techniques and suggestions for optimizing the results.

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Map of diffuse interstellar bands Courtesy of T.W. Lan, G. Zasowski, B. Ménard, SDSS and 2MASS/UMass/IPAC-Caltech/NASA/NSF

Astronomers Map Mysterious Molecules in our Galaxy

January 12, 2015 10:20 am | by Phil Sneiderman, Johns Hopkins University | News | Comments

By analyzing the light of hundreds of thousands of celestial objects, astronomers have created a unique map of enigmatic molecules in our galaxy that are responsible for puzzling features in the light from stars, called diffuse interstellar bands. DIBs have been a mystery ever since they were discovered in 1922 — exactly which of the many thousands of possible molecules are responsible for these features?

John Wass is a statistician based in Chicago, IL

Qlucore Omics Explorer: Analysis in an Instant

January 8, 2015 4:00 pm | by John A. Wass, Ph.D. | Articles | Comments

Qlucore is a software platform for the analysis of genomics, proteomics and related data. As with most statistical and genomics software, it generates an immediate graphic for most analyses. Its specific areas of use include gene expression, protein arrays, DNA methylation, miRNA, proteomics, and pattern and structure identification in multivariate data.

Peter Boogaard is the founder of Industrial Lab Automation and chairman of the Paperless Lab Academy.

2015 Promises Major Milestones and Demands for Change

January 7, 2015 12:28 pm | by Peter J. Boogaard | Articles | Comments

Despite the fact that industries won’t change working processes unless there is a mandatory need to do so, major milestones are expected in 2015 in the battle to adopt data and standardization in our scientific community. The need for deployment of these integration standards to enable efficient sharing of knowledge across our internal and external partners is re-enforced by regulatory bodies.

The species used in a Rice University genetic study of mice were collected from 15 locations in Europe and Africa. The green region indicates the range of Mus spretus, the Algerian mouse, while the blue region indicates the range of Mus musculus domesticu

Big Data Analysis Reveals Shared Genetic Code between Species

December 18, 2014 11:32 am | by Mike Williams, Rice University | News | Comments

Researchers have detected at least three instances of cross-species mating that likely influenced the evolutionary paths of “old world” mice, two in recent times and one in the distant past. They think these instances of introgressive hybridization are only the first of many needles waiting to be found in a very large genetic haystack. The finding suggests that hybridization in mammals may not be an evolutionary dead end.

Michael Boruta is Optical Spectroscopy Product Manager at ACD/Labs

Accessibility of Data and Application of Algorithms to Provide Insights in Predictive Analytics

December 15, 2014 11:56 am | by Michael Boruta, ACD/Labs | Blogs | Comments

Although there are a diverse range of applications for predictive analytics in R&D, two common basic requirements are data and insight. Data may be generated by running experiments/analyses, or re-applied from previous work when available. Insights come from application of knowledge — both explicitand tacit. There are a variety of roles for informatics in predictive analytics...

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Professor Tandy Warnow developed a new statistical method that sorts genetic data to construct better species trees detailing genetic lineage. Courtesy of L. Brian Stauffer

Sophisticated New Statistical Technique helps Map Species' Genetic Heritage

December 12, 2014 5:50 pm | by Liz Ahlberg, University of Illinois | News | Comments

Where did the songbird get its song? What branch of the bird family tree is closer to the flamingo — the heron or the sparrow? These questions seem simple, but are actually difficult for geneticists to answer. A new, sophisticated statistical technique can help researchers construct more accurate species trees detailing the lineage of genes and the relationships between species.

Madhu Sudan and his colleagues have begun to describe theoretical limits on the degree of imprecision that communicating computers can tolerate, with very real implications for the design of communication protocols. Courtesy of Jose-Luis Olivares/MIT

New Theory could Yield More Reliable Communication Protocols

December 12, 2014 5:23 pm | by Larry Hardesty, MIT | News | Comments

Communication protocols for digital devices are very efficient but also very brittle: They require information to be specified in a precise order with a precise number of bits. If sender and receiver — say, a computer and a printer — are off by even a single bit relative to each other, communication between them breaks down entirely.

The National Medal of Science and National Medal of Technology and Innovation medals ready to be presented to awardees. Courtesy of Sandy Schaeffer, NSF

National Medals of Science, Technology and Innovation Presented

November 25, 2014 12:00 pm | by NSF | News | Comments

At a White House ceremony on November 20, 2014, President Obama presented the National Medal of Science and National Medal of Technology and Innovation to individuals who have made outstanding contributions to science and engineering. The awards are the nation's highest honors for achievement and leadership in advancing the fields of science and technology.

John Wass is a statistician based in Chicago, IL.

Exploration and Analysis of DNA Microarray and Other High-Dimensional Data

November 18, 2014 3:10 pm | by John A. Wass, Ph.D. | Articles | Comments

The introduction of newer sequencing methodologies, DNA microarrays and high-throughput technology has resulted in a deluge of large data sets that require new strategies to clean, normalize and analyze the data. All of these and more are covered in approximately 300 pages with extraordinary clarity and minimal mathematics.

Mark Anawis is a Principal Scientist and ASQ Six Sigma Black Belt at Abbott.

Applications for Randomness

November 17, 2014 8:49 am | by Mark A. Anawis | Blogs | Comments

The mathematician, Robert R. Coveyou, said: “The generation of random numbers is too important to be left to chance.” Random numbers are used in sampling, simulations, modeling, data encryption, gambling and even musical composition. A random number is one selected from a set of equally possible values. Any sequence of random numbers must be statistically independent of the others.

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JMP 11: Remarkable Statistics, Graphics and Integration Designed for the Technician, Scientist, Engineer and Businessperson

JMP 11: Remarkable Statistics, Graphics and Integration

November 7, 2014 10:30 am | by John A. Wass, Ph.D. | Articles | Comments

It should come as no surprise to readers of this column that JMP is a personal favorite and, along with SAS, one of my most-used programs. There are a number of reasons for this. Of the many advantages that most packages can offer, breadth and depth of the statistics offered, quality of the diagnostics, interconnectivity of graphics with both data and analyses, and ease-of-use issues are uppermost in my mind as most desirable.

QT 2.5 Chemometrics Software

Symbion QT 2.5 Chemometrics Software

November 6, 2014 3:27 pm | Symbion Systems | Product Releases | Comments

Symbion QT 2.5. chemometrics software provides Parametric Data Cleaning, a technique that automates the handling of data compromised by excessive noise or other artifacts. Key cleaning parameters are under the control of the analyst, allowing chemometric optimization under a wide range of analytical situations.

GeneSpring Pathway Architect Software

GeneSpring Pathway Architect Software

November 3, 2014 11:44 am | Agilent Technologies | Product Releases | Comments

GeneSpring Pathway Architect software is designed to enable faster discovery of complex relationships across multi-omic data. Designed for researchers focused on genomics, proteomics, metabolomics, transcriptomics or any combination of life science disciplines, the package includes GeneSpring GX and Mass Profiler Professional, as well as Pathway Architect.

Origin and OriginPro 2015 Data Analysis and Graphing Software

Origin and OriginPro 2015 Data Analysis and Graphing Software

October 30, 2014 12:45 pm | Originlab Corporation | Product Releases | Comments

Origin and OriginPro 2015 are software applications for data analysis and publication-quality graphing that are tailored to the needs of scientists and engineers. The applications are designed to offer an easy-to-use interface for beginners, and the ability for advanced users to customize analysis and graphing tasks using themes, templates, custom reports, batch processing and programming.

Huygens Titan Image Search Engine

Huygens Titan Image Search Engine

October 28, 2014 10:43 am | Scientific Volume Imaging | Product Releases | Comments

Huygens Titan is lightweight software that indexes, finds and shows 2-D to 5-D microscopic image data. It can read all common microscope formats from any folder and subdirectory on any location to which a user has access. The software does not alter or move images.

Prescribed oceanic patterns are useful for predicting large weather anomalies. Prolonged dry or wet spells over certain regions can reliably tell you whether, for instance, North America will undergo an oceanic weather pattern such as the El Nino or La Ni

Time Machine Reveals Global Precipitation Role in Major Weather Events

October 16, 2014 2:53 pm | by Michael Price, San Diego State University | News | Comments

During the 1930s, North America endured the Dust Bowl, a prolonged era of dryness that withered crops and dramatically altered where the population settled. Land-based precipitation records from the years leading up to the Dust Bowl are consistent with the telltale drying-out period associated with a persistent dry weather pattern, but they can’t explain why the drought was so pronounced and long-lasting.

This solar flare was shot with one of the cameras on the NASA SDO satellite on June 10, 2014. Courtesy of NASA/SDO

Solar Explosions inside a Computer: Predicting Solar Flares

September 25, 2014 4:30 pm | by Barbara Vonarburg, ETH | News | Comments

Strong solar flares can bring down communications and power grids on Earth. By demonstrating how these gigantic eruptions are caused, physicists are laying the foundations for future predictions. The shorter the interval between two explosions in the solar atmosphere, the more likely it is that the second flare will be stronger than the first one.

Close-ups of an experiment conducted by John Bush and his student Daniel Harris, in which a bouncing droplet of fluid was propelled across a fluid bath by waves it generated. Courtesy of Dan Harris

Fluid Mechanics: New Math Suggests Alternative to Quantum Orthodoxy

September 15, 2014 3:43 pm | by Larry Hardesty, MIT | News | Comments

The central mystery of quantum mechanics is that small chunks of matter sometimes seem to behave like particles, sometimes like waves. For most of the past century, the prevailing explanation of this conundrum has been what’s called the “Copenhagen interpretation” — which holds that, in some sense, a single particle really is a wave, smeared out across the universe, which collapses into a determinate location only when observed.

This undated image provided by NASA shows the ozone layer over the years, September 17, 1979, top left, October 7, 1989, top right, October 9, 2006, lower left, and October 1, 2010, lower right. Earth’s protective but fragile ozone layer is finally starti

Scientists say Ozone Layer is Recovering

September 10, 2014 4:17 pm | by Seth Borenstein, AP Science Writer | News | Comments

Earth's protective but fragile ozone layer is beginning to recover, largely because of the phase-out since the 1980s of certain chemicals used in refrigerants and aerosol cans, a U.N. scientific panel reported September 10, 2014, in a rare piece of good news about the health of the planet. Scientists said the development demonstrates that, when the world comes together, it can counteract a brewing ecological crisis.

The software (the SAFE Project) uses artificial intelligence to allow a computer to perceive sounds like a human being.

Training Computers to Understand the Language of Musicians

September 10, 2014 4:07 pm | by Birmingham City University | News | Comments

New software launched by researchers at Birmingham City University aims to reduce the long periods of training and expensive equipment required to make music, while also giving musicians more intuitive control over the music that they produce. The developed software, showcased at the British Science Festival, trains computers to understand the language of musicians when applying effects to their music.

Sandia National Laboratories managers Alex Roesler, left, and Luke Purvis, center, and systems analyst Jarret Lafleur shown inside a Bank of Italy vault in a historic Livermore, California, building, studied 23 high-value heists that occurred in the last

National Security: Lessons Learned Drawn from Perfect Heists

August 25, 2014 12:00 pm | by Sandia National Laboratories | News | Comments

The Antwerp Diamond Center theft and other sophisticated, high-value heists show that motivated criminals can find ways to overcome every obstacle between them and their targets. Can the Energy and Defense departments, responsible for analyzing, designing and implementing complex systems to protect vital national security assets, learn from security failures in the banking, art and jewelry worlds? Sandia Labs set out to answer that question

SigmaPlot Version 13

SigmaPlot 13 Scientific Data Analysis and Graphing Software

July 29, 2014 12:46 pm | Systat Software, Inc. | Product Releases | Comments

SigmaPlot Version 13 is a scientific data analysis and graphing software package with features that include Forest plots, which combine the results of like studies to improve statistical significance, and Kernel Density — a smooth probability distribution plot — as well as Analysis of Covariance (ANCOVA), which includes the effects of “nuisance” variables, and Principal Components Analysis (PCA) to determine the major data relationships.

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